Otsuka Pharmaceutical Company, Limited

Proteus Digital Health, Inc.

Other

University of California

Robert Azevedo

Robert Duck

Jeremy Frank

Peter Bjeletich

Hooman Hafezi

Benedict Costello

Eric Snyder

Iliya Pesic

Raymond H Schmidt

Kurt Scheinpflug

Nikhil Pargaonkar

Chris Dong

Hiren Patel

Nikolaus Leist

Timothy Robertson

Albert P Pisano

Lawrence W Arne

Todd Thompson

Aditya Dua

William A Weeks

David C Walther

Michael T Mueller

Neraj P Bobra

Ronny X Li

David R Myers

Matthew Wasilik

A system, a wearable device, and a method are provided which can increase the accuracy of physiological metrics while detecting if the patient ingested digital medicine and/or improve performance of the wearable device. The wearable device can comprise machine executable instructions that when executed by the processor, cause the processor to perform various algorithms, such as, for example, at least one of a step count algorithm, a body angle algorithm, a heart rate algorithm, a peak finder algorithm, an adaptive thresholding algorithm, a heart rate variability algorithm, a R-R cleaning Algorithm, a deltaR-R cleaning algorithm, a merge twin interval algorithm, a split tall intervals algorithm, an absorb short intervals algorithm, a bimodal detection algorithm, and a resting algorithm.

Low power receiver for in vivo channel sensing and ingestible sensor detection with wandering frequency

Various methods and apparatuses are presented for an ingestible capsule that includes a digital, ingestible sensor component&#x2014;or ingestible sensor&#x2014;embedded into the capsule. The ingestible sensor component may be configured to activate upon coming into contact with conductive fluid, such as a body's stomach fluid. Once activated, the ingestible sensor component may be configured to perform various tasks, such as transmitting one or more signals and obtaining biometric data about the body that ingested the capsule.

Methods for manufacturing capsules with ingestible event markers

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Communication system with enhanced partial power source and method of manufacturing same

A re-wearable wireless device includes a reusable component to be secured to a disposable component. The reusable component includes a sensor interface to receive signals from an electrode secured to a living subject and monitors physiological and physical parameters associated with the living subject and a cellular wireless communication circuit. An adhesive base the device includes a first adhesive layer and a second adhesive layer partially covering the first adhesive layer around a perimeter thereof, where the first and second adhesive layers include different adhesives. A method of establishing a link between two wireless devices is also disclosed, where a first wireless device with an insignia representing a communication channel address identification is provided. An image of the insignia is captured with a mobile telephone computing device comprising an image sensor. The captured image is processed to extract the communication channel address identification represented by the insignia.

Re-wearable wireless device

An infrared sensor with at least one cantilever beam functionalized with chitin, chitosan or their derivatives that can be tailored to be sensitive to certain IR bands for detection and does not require cooling is described. The functional layers expand differently than the structural layer of the cantilever beam causing the beam to bend in response to exposure to infrared radiation. The sensor can be adapted to optical, piezoresistive, capacitive and piezoelectric methods of detect beam deflection. Sensitivity can be increased with a reflective layer to increase the absorption of infrared radiation by the functional layer.

Chitin-based cantilever bimorphs and readout devices

Growing community of inventors

Albany, CA, United States of America

Robert Azevedo