Burroughs Wellcome Co.

Robert Arthur Maxwell

Eric Walton

Frederick C Copp

Compounds containing the N-m-methoxybenzyl-N,N-dimethyl-N-2-hydroxyethylammonium cation and non-toxic salts of the N-m-methoxybenzyl-N,N-dimethyl-N-ethylammonium cation. The compounds have antiarrhythmic properties, and are useful specifically as antifibrillatory agents.

Quaternary ammonium compounds useful as antifibrillatory agent

N- substituted - guanidines having antifibrillatory activity; non-toxic salts thereof; pharmaceutical compositions thereof; and their use in treating cardiac fibrillations.

Substituted guanidine compounds in the treating of arrythmias

Acid addition salts of N-p-methylbenzyl-N',N'-dimethylguanidine and of N-p-methoxybenzyl-N',N'-dimethylguanidine. The compounds have antiarrhythmic properties, and are useful specifically as antifibrillatory agents.

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Armonk, NY, United States of America

Robert Arthur Maxwell