Ge Healthcare Limited

Ge Healthcare UK Limited

Amersham Plc

Robert Arnold Jessop

Philip John Meyler

Christopher Jones

Michael Roger Looker

Malcolm John Hatcher

Michael Keith Page

The invention concerns scintillation proximity assays performed in multiwell plates where a charge coupled device is used to image the wells. Conventional phosphors emit blue light (350&#x2013;450 nm) which is absorbed by yellow or brown assay components. This problem is addressed by the use of phosphors that emit radiation of longer wavelength (480&#x2013;900 nm).

Scintillation proximity test

A multi-modality fluorescence reference plate comprising wells coated with a fluorogenic compound is described, together with a method of producing such a plate. The plate has utility for calibrating fluorescent plate readers and imaging systems for measuring steady-state fluorescence, time-resolved fluorescence, fluorescence lifetime and/or fluorescence polarisation.

Fluorescence reference plate

The invention concerns scintillation proximity assays performed in multiwell plates where a charge coupled device is used to image the wells. Conventional phosphors emit blue light (350-450 nm) which is absorbed by yellow or brown assay components. This problem is addressed by the use of phosphors that emit radiation of longer wavelength (480-900 nm).

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Cardiff, United Kingdom

Robert Arnold Jessop