John Wyeth Brother, Limited

Robert Anthony Newberry

Brian John Bushell

The invention concerns diarylpyrazole lower alkanoic acids and derivatives which are pharmacologically efficacious as anti-inflammatory agents. The said compounds can be represented by the formula ##STR1## in which one of D, E, F and G represents hydrogen, one is a lower aliphatic acid radical or derivative thereof and the remaining two of D, E, F and G are aryl or heteroaryl radicals.

1,3-Diaryl-pyrazol-4-acrylic acid and derivatives

This invention relates to novel thiazole derivatives having the formula: ##SPC1## Wherein R represents an unsubstituted or substituted aryl radical; R.sup.1 and R.sup.2 independently represent hydrogen or lower alkyl; R.sup.3 represents hydrogen or lower alkyl; and --COZ represents an amide group; a carboxylic acid group or an ammonium or pharmaceutically acceptable alkali metal or alkaline earth metal salt thereof; or an ester group of formula --COOR.sup.4 wherein R.sup.4 represents an alkyl, aralkyl or aryl radical, which exhibit antilipemic activity.

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Portsmouth, United Kingdom

Robert Anthony Newberry