The Procter Gamble Company

Family Health International

Robert Allan Johnson

William Robert Ouellette

David C Sokal

Bruce Neil Hall

Carol L Joanis

James D Reed

George A M Butterworth

A vaginal drug delivery system includes a device formed of porous material that holds a flowable therapeutic formulation. The device, preferably in a soft, prewetted state, is inserted into the vagina to reside typically at or near the cervix where it continuously releases the flowable therapeutic formulation through its outer surface which is in contact with the vaginal surfaces. In operation, the flowable therapeutic formulation migrates via capillary forces from a reservoir that is centrally located in the device and through a covering that envelopes the reservoir.

Vaginal drug delivery system and method

An absorbent, low-linting fibrous structure comprising an entangled web of synthetic fibers, wherein fibers of at least one of said top surface and said bottom surface are surface bonded, such as by thermal or adhesive bonding. The web is absorbent, has low density, is resistant to linting, and can retain structural integrity at high temperatures. The structure can be made by forming a web of synthetic fibers, entangling the fibers of the web, such as by needling or hydroentangling, and bonding the fibers at the surface of the web by thermal or adhesive bonding.

Surface bonded entangled fibrous web and method of making and using

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Turnersville, NJ, United States of America

Robert Allan Johnson