Audioptics Medical Incorporated

Dalhousie University

Robert Adamson

Jeremy Brown

Manohar Bance

Daniel MacDougall

Zahra Torbatian

Christopher Samson

Katherine Latham

Daniel Ryan Macdougall

Acoustic immittance and other characteristics of ears may be determined by measuring eardrum displacements resulting from application of pressure to the eardrum. For example, optical coherence tomography may be applied to monitor eardrum displacements responsive to a sound. The pressure corresponding to the sound is measured by a suitable instrument such as a microphone. The measured displacements and pressures may be processed to obtain a measure of immitance.

Systems and methods for middle ear immittance testing

Encoded transmit signals are provided to an ultrasound array such diverging ultrasound waves are sequentially transmitted. Each diverging ultrasound wave is generated by a respective set of encoded transmit signals, where each set of encoded transmit signals is encoded by a respective row of an N×N invertible orthogonal matrix. Only a selected subset of M rows, with N<M, is employed to encode the transmit signals. Sets of receive signals detected in response to the transmitted diverging ultrasound waves are decoded via a transposed matrix generated based on the invertible orthogonal matrix, with each set of decoded receive signals being associated with insonification via a subset of the ultrasound array elements in the fixed aperture. Synthetic aperture beamforming is performed on the decoded receive signals to generate an ultrasound image.

Systems and methods of sparse orthogonal diverging wave ultrasound imaging

Systems and methods are provided for performing OCT vibrography based on the synchronization of components of the OCT vibrography system. An A-scan trigger is employed to synchronize the operation of the scanning subsystem that scans the sample beam and an acoustic stimulus source that generates an acoustic stimulus for vibrographic measurements. The acoustic stimulus source is controlled such that when the scanning subsystem dwells on an imaging line selected for vibrography measurements, the acoustic stimulus is generated over a plurality of A-scans and the phase of the acoustic stimulus is locked to the A-scan trigger, such that the phase of the acoustic stimulus is incrementally modified with each A-scan. The accumulation of the acoustic phase is therefore synchronized to the A-scan trigger. The synchronization, providing synchronized acoustic phase evolution during each acoustic phase waveform cycle, permits the use of the OCT vibrography system for simultaneous anatomical and functional imaging.

Systems and methods for swept-source optical coherence tomographic vibrography

Systems and methods are provided for performing phase-sensitive optical coherence tomographic (PS-OCT) measurements involving the vibrographic response of an acoustic stimulus. Detected signals are processed to provide sampled time-dependent vibrographic data characterizing a vibratory amplitude and phase response over one or more periods of the acoustic stimulus. The sampled time-dependent vibrographic data is processed to suppress the sinusoidal signal component associated with the acoustic stimulus, thereby providing a residual data associated with noise. The residual data is processed to obtain an estimate of the motion noise, and the motion noise is subtracted from the sampled time-dependent vibrographic data in order to provide noise-corrected vibrographic data. The noise-corrected vibrographic data can be processed to obtain one or more vibrographic measures and/or one or more images.

Systems and methods for performing phase-sensitive acoustic vibrations using optical coherence tomography

High-frequency ultrasound imaging can be performed with greater quality and suppressed grating lobes by using methods and systems for effectively reducing the temporal length of transmit grating lobe signals in received ultrasound echoes. Systems and methods are provided for improved high-frequency ultrasound imaging. In various aspects, the method of shortening the time domain of grating lobe signals comprises splitting an array of N transmit elements into K sub-apertures. In further aspects, the grating lobes are suppressed by performing signal processing of the shortened grating lobe signals. In certain aspects, the signal processing method comprises weighting the samples by a calculated phase coherence factor.

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Halifax, Canada

Robert Adamson