Ranier Limited

Ranier Limited, Fountain House

Robert Adam Snell

Geoffrey Thomas Andrews

Scott Johnson

Jonathan Lawson

Martin Cable

A process for making a polymeric product having a gradual variation in modulus through at least a portion of the product is disclosed together with an artificial spinal disc formed using the process.

High precision manufacture of polyurethane products such as spinal disc implants having gradual modulus variation

An instrument for preparing a surface of a vertebra, such as a vertebral endplate, for receipt of a spinal disc implant. The instrument includes a working tool with implements on one or more surfaces of the working tool that act on the vertebral surface. The instrument includes a rotary-to-linear translation system to cause the working tool to move; for example, from side-to-side, top-to-bottom, or along a path that includes side-to-side and top-to-bottom aspects. The rotary-to-linear translation system may include a drive shaft having a cam pin at a distal end, and a cam follower slot at an anterior end of the working tool.

Vertebral surface preparation instrument

High precision manufacture of polyurethane products such as spinal disc implants having a gradual modulus variation

An instrument for preparation of vertebral endplates and a method of preparing a surface of a vertebral endplate are described. The instrument includes a body having a frame, an endplate preparation member supported by the body, and a pivot point. A tilt axis is perpendicular to and intersects a sweep axis at the pivot point. The endplate preparation member is coupled to the frame and controllably pivotable in an arc about the first tilt axis to change a tilt of the endplate preparation member. The endplate preparation member is also controllably pivotable in an arc about the sweep axis while maintaining the tilt of the endplate preparation member. By sweeping the endplate preparation member at incrementally larger tilt angles, recesses in a vertebral endplate surface are gradually formed, which may allow greater precision and control of a depth of the recesses and reduce stress on the vertebral endplate, as opposed to more aggressive techniques.

Endplate preparation instrument

The present invention relates to a balloon portion for a balloon catheter for radially expanding a vessel in the body of a mammal, which catheter comprises a tube portion with a passage therethrough and a hollow expandable balloon portion defined by a fluid impervious wall and secured to the tube portion, which balloon portion can be inflated and deflated by means of a fluid passed through the passage, characterized in that: The invention also provides a balloon catheter in which the balloon portion is a balloon of the invention. The invention further provides a method for making the balloon catheter of the invention.

Balloon catheter

A method of forming a reticulated coating on a substrate includes providing an agglomerate dispersion of a first polymer in a polar liquid carrier on a surface of the substrate, and evaporating the liquid carrier to form the coating.

Reticulated coatings

A method of manufacturing a balloon portion for a balloon catheter for radially expanding a vessel in the body of a mammal, which catheter comprises a tube portion with a passage therethrough and a hollow expandable balloon portion defined by a fluid impervious wall and secured to the tube portion, which balloon portion can be inflated and deflated by means of a fluid passed through the passage, such that:

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Newmarket, United Kingdom

Robert Adam Snell