Corning Glass Works

Robert A Oppermann

Ralph A Messing

Milton M Takeguchi

William S Ramsey

Lynn B Simpson

A method for the continuous culturing of microbes in a plug-flow reactor which comprises the steps of:

Method for continuous culturing of microbes

Bacteria immobilized by adsorption on an inorganic carrier are stabilized by carrying out the adsorption procedure in the presence of from about 1 to about 20% weight per volume of sucrose of nonfat dry milk solids and lyophilizing the adsorbed bacteria.

Stabilization of immobilized bacteria

Immobilized microbe composite comprising a porous, high surface area inorganic support having a controlled population of microbes bonded to the internal surfaces of the pores, the support being water insoluble, non-toxic to the microbes, and having a controlled porosity such that at least 70% of the pores, on a pore size distribution basis, have a pore diameter at least as large as the smallest major dimension of the microbes but less than about five times the largest major dimension of the microbes. The composites are especially useful in situations requiring a high biomass surface within a relatively small volume.

High surface low volume biomass composite

Immobilized microbe composite comprising a porous, high surface area inorganic support having a controlled population of fungus-like microbes bonded to the internal surfaces of the pores, the support being water insoluble, non-toxic to the microbes, and having a controlled porosity such that at least 70% of the pores, on a pore size distribution basis, have a pore diameter at least as large as the smallest diameter of the fungal spore but less than about sixteen times the largest spore diameter. The composites are especially useful in situations requiring a high biomass surface within a relatively small volume.

High surface low volume fungal biomass composite

Immobilized microbe composite comprising a porous, high surface area inorganic support having a controlled population of yeast cells bonded to the internal surfaces of the pores, the support being water insoluble, non-toxic to the cells, and having a controlled porosity such that at least 70% of the pores, on a pore size distribution basis, have a pore diameter at least as large as the smallest dimension of the cells but less than about four times the largest dimension of the cells. The composites are especially useful in situations requiring a high biomass surface within a relatively small volume.

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Painted Post, NY, United States of America

Robert A Oppermann