Phoenix Biotechnology, Inc.

University of Texas System

New Chapter Inc.

The Procter Gamble Company

Other

University of California

Coastside Bio Resources

Robert A Newman

Otis Crandell Addington

Peiying Yang

Paul Schulick

Thomas Newmark

Abdul R Khokhar

Bharat B Aggarwal

Donald C Lo

Linda S Kaltenbach

Richard J Obiso

Irwin H Krakoff

Michael G Rosenblum

Jose R Matos

Jonathan A Ellman

Peter Donald Collin

Peter J Kelleher

Zahid H Siddik

Nicholas J Donato

John S McMurray

Raymond J Budde

Victor A Levin

James L Murray

David C Sample

Gary E Gallick

Margot Perez

Nicholas D Donato

O Crandell Addington

A subcritical liquid extraction process for the production of oleandrin or oleandrin-containing extract is provided. The process provides improvements over other methods of preparing oleandrin-containing extract. The extract, pharmaceutical compositions, dosage forms and nutraceutical compositions comprising oleandrin or said extract are provided. Methods of treating diseases, disorders or conditions that are therapeutically responsive to oleandrin are also provided.

Extract containing oleandrin and method of production thereof

A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin or digoxin is used to treat the viral infection or the disease state of said viral infection.

Method and compositions for treating Coronavirus infection

A method of treating a triterpene-responsive condition, disease or disorder in a subject by administration of an improved triterpene-based composition is provided. An improved triterpene-based composition comprising at least two or at least three triterpenes present at a molar ratio as described herein is also provided.

Method of and improved composition for treating triterpene-responsive conditions, diseases or disorders

A method of treating equine encephalitis is provided. A composition having at least one cardiac glycoside, such as oleandrin, is used to treat a viral infection causing the encephalitis. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.

Method and compositions for treating equine encephalitis

A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (genus),genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.

Method and compositions for treating viral infection

A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (genus),genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can futher include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.

A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.

A method of treating neurological condition in a subject by administration of a neuroprotective composition of a mixture of two or more triterpenes. Alzheimer's disease, Huntington's disease, stroke or Parkinson's disease are treated by administering a therapeutically effective amount of the neuroprotective composition to a subject.

Method of treating neurological conditions with extract ofspecies orspecies

A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (genus),genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can futher include at least one triterpene. Alternatively, the composition comprises at least one, at leat two, or at least three triterpenes.

A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin is used to treat viral infection.

Method and compostitions for treating coronavirus infection

A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae, Flaviviridae or Togaviriade family, is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene.

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Surry, ME, United States of America

Robert A Newman