Fritzsche Dodge & Olcott Inc.

Usv Pharmaceutical Corporation

Robert A Mack

Brian J Willis

Philip A Christenson

Bernard Loev

Vasil St Georgiev

John H Musser

Richard E Brown

Compounds useful as fragrance materials having the structure ##STR1## wherein each of R.sub.1, R.sub.2, and R.sub.3 are hydrogen or methyl can be prepared by reacting a halogen-containing cyclohexane, having the structure ##STR2## wherein each of R.sub.1, R.sub.2, and R.sub.3 are hydrogen or methyl and X is a halogen, with a reagent capable of effecting intramolecular cyclization.

Ambrinol and its homologues

The present invention relates to novel compounds useful as fragrance materials which have the structure ##STR1## wherein the dashed line may be either a carbon-carbon single bond or a carbon-carbon double bond; R.sub.1, R.sub.2 and R.sub.3 are each the same or different and each represents hydrogen or methyl; and X is halogen. The invention also provides methods of preparing these compounds from readily available cyclohexene derivatives and fragrance compositions which include the compounds.

Halogen containing cyclohexane derivatives, methods of preparation and

Therapeutic compositions containing as active principle, a benzoxazindione or pharmaceutically-acceptable acid addition salt thereof are useful in the treatment of allergy.

Process for treatment of allergic conditions with benzoxazinediones

New triazolobenzoxazinones are described as well as the use thereof as anti-allergenic agents.

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Valley Stream, NY, United States of America

Robert A Mack