American Cyanamid Company

Robert A Hardy, Jr

Nicanor Quinones Quinones

Jay Donald Albright

John P Dusza

William B Wright, Jr

Rolf Paul

John J Brown

Patrick T Izzo

John A Brockman

Jannie S Baker

This invention is concerned with 5-substituted[1,2,4]triazolo[1,5-c]pyrimidin-2-amines selected from those of Formula I, which are active as antiasthma agents.

5-substituted[1,2,4]triazolo[1,5-c]pyrimidin-2-amines

This disclosure describes novel 5-,6- and 8-(phenyl and substituted phenyl)-1,2,4-triazolo[4,3-a]pyrazines which posses utility as anxiolytic agents.

Novel (substituted phenyl)-1,2,4-triazolo (4,3-A)pyrazines and novel

This disclosure describes 8-substituted-4-phenyl-1-oxa-8-azaspiro[4,5]dec-3-en-2-ones and 8-substituted-4-phenyl-1-oxa-8-azaspiro[4,5]decan-2-ones useful as analgesic or neuroleptic agents.

4-Aryl-1-oxa-8-azaspiro[4,5]dec-3-en-2-ones

This disclosure describes novel 5-, 7-, and 8-(substituted-phenyl)-1,2,4-triazolo[4,3-c]pyrimidines and 5-, 7-, and 8-(substituted-phenyl)-1,2,4-triazolo[1,5-c]pyrimidines and their use as anxiolytic agents.

(Substituted-phenyl)-1,2,4-triazolo[4,3-c]pyrimidines and

This disclosure describes substituted 1,2,4-triazolo[1,5-a]pyrimidines and substituted 1,2,4-triazolo[4,3-a]pyrimidines which possess anxiolytic activity.

(Substituted-phenyl)-1,2,4-triazolo[4,3-a]-pyrimidines and

This disclosure describes substituted 11-piperazinyl-5H-pyrrolo[2,1-c][1,4]benzodiazepines useful as anti-psychotic or neuroleptic agents.

5H-Pyrrolo[2,1-c][1,4]benzodiazepine derivatives

The compounds, 11-(4-piperidyl)-5H-dibenzo[b,e] [1,4]diazepines, intermediates and methods of preparation thereof are described. They are useful as neuroleptic agents.

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Ridgewood, NJ, United States of America

Robert A Hardy, Jr