Smithkline Beecham Corporation

Cephalon, Inc.

Robert A Daines

Israil Pendrak

William D Kingsbury

Pamela A Chambers

Dalia R Jakas

John P Mallamo

Jack Dale Leber

Kelvin C Sham

Joseph Weinstock

Siegfried B Christensen, Iv

Sankar Chatterjee

Kurt A Josef

Derek D Dunn

Zi-Qiang Gu

Martha S Head

Kelvin Kin-Cheong Sham

Israel Pendrak

Siegfired B Christensen, Iv

This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.

Fatty acid synthase inhibitors

Novel indole derivatives, pharmaceutical compositions containing these compounds and their use as inhibitors of the fatty acid synthase FabH are disclosed.

Indole compounds

This invention relates to the use of certain indole compounds, which are active as inhibitors of the fatty acid synthase FabH, for the treatment of bacterial infections.

Indole compounds useful for treating bacterial infections

This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH useful in treating bacterial infections.

Pharmaceutical compositions and methods of inhibiting calpain using novel indolecarboxamides are disclosed.

Indolecarboxamides, pharmaceutical compositions and methods of inhibiting calpain

Quinoline- and naphthalenecarboxamides, pharmaceutical compositions and

The present invention is directed to quinoline-containing .alpha.-ketoamide inhibitors of cysteine and serine proteases are disclosed. Methods for making these compounds, and methods for using the same are also disclosed.

Quinoline-containing .alpha.-ketoamide cysteine and serine protease

Pharmaceutical pyridine compounds

Process for making phenylthiomethylpyridinylalkenoates

##STR1## This invention relates to compounds of formula (I) which are useful as leukotriene antagonists.

Pyridine compounds for treating leukotriene-related diseases

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Lansdale, PA, United States of America

Robert A Daines