Avidity Biosciences, Inc.

Merck Sharp + Dohme Corp.

Rob Burke

Venkata Ramana Doppalapudi

Michael Caramian Cochran

Beatrice Diana Darimont

Andrew John Geall

Barbora Malecova

David Sai-Ho Chu

Gulin Erdogan Marelius

Michael David Hood

Yunyu Shi

David Sala Cano

Palani Balu

Rachel Elizabeth Johns

Hanhua Huang

Arthur A Levin

Joel Daniel Arias

Matthew G Stanton

Steven L Colletti

Thomas Joseph Tucker

Weimin Wang

Rubina G Parmar

David M Tellers

Kathleen B Calati

Boyoung Kim

Philip Kovach

Jeffrey G Aaronson

Jeffery G Aaronson

Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).

Compositions and methods of treating muscle dystrophy

Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Nucleic acid-polypeptide compositions and uses thereof

Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Compositions and methods of treating muscle atrophy and myotonic dystrophy

Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).

Compositions and methods of treating facioscapulohumeral muscular dystrophy

Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.

Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.

Nucleic acid-polypeptide compositions and methods of inducing exon skipping

Compositions and methods of treating Facioscapulohumeral muscular dystrophy

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Encinitas, CA, United States of America

Rob Burke