Shilpa Medicare Limited

Rizwan Ahmed

Nagaraju Dasari

Shivakumar Pradeep

Akshaykant Chaturvedi

Krishnamurthy Toppaladoddi

Pradeep Shivakumar

Guptha Chinni Guru Deva

Ravi Kishore

The present invention relates to a stable, non-aqueous liquid, formulation consisting essentially of melphalan, or a pharmaceutical acceptable salt thereof; and one or more solvents selected from group consisting of dimethyl acetamide, polyethylene glycol, ethanol, propylene glycol, dimethyl sulfoxide, N-methylpyrrolidone and glycerol; wherein said formulation is free of antioxidants, organic acid and added chloride ions; and the process for preparation thereof.

Stable melphalan liquid injectable formulations

The present invention relates to polymorphic forms of 5-Azacytidine and the process for preparation thereof. The present invention further relates to Crystalline 5-azacytidine 5 designated as Form-SA-1 characterized by an X-ray powder diffraction pattern having at least four characteristic diffraction angle peaks at about 12.00, 12.60, 13.90, 15.15 and 31.40&#xb1;0.20 2&#x3b8;&#xb0;, which is useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment of myelodysplastic syndrome.

Formulation of 5-azacytidine

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Vizianagaram, India

Rizwan Ahmed