Sclavo Spa

Rivo Presentini

Diana Boraschi

Guido Antoni

Aldo Tagliabue

Luca Parente

Kenneth G Mugridge

Cristina Becherucci

Mauro Perretti

Egle Solito

The synthetic peptide of formula (I) H-Ser-His-Leu-Arg-Lys-Val-Phe-Asp-Lys-OH (SEQ ID NO. 1) and its physiologically acceptable organic or inorganic salts are novel. The synthetic peptide (I), whose amino acid sequence corresponds to that of the sequence 204-212 of human lipocortin V, shows in vitro the capability of inhibiting the prostaglandin E2 release and in vivo an antiinflammatory activity. The peptide and its organic and inorganic salts are useful as therapeutic agents for the treatment of dermatological and collagen inflammatory infections.

Antiinflammatory peptide derived from human lipocortin V

Synthetic peptide with human interleukin 1 activity, which peptide can be used as a stimulant of the immune functions and can be defined by the general formula:

Synthetic peptide with human interleukin 1 activity

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Siena, Italy

Rivo Presentini