Adlens Limited

Alcon, Inc.

Ttp Plc

Rita Stella

Robert Edward Stevens

Jon Nisper

Derek Paul Forbes Bean

Peter Lee Crossley

Tom Worsley

Ashutosh Kumar

Thomas Jacoby

Richard Wilhelm Janse Van Rensburg

William Guest

John Alfred Campin

Nicholas James Wooder

Costin Eugene Curatu

Giles Hugo William Sanders

Luis Diaz-Santana

Samuel Pollock

Richard Lintern

Abi Clair Graham

A method of assembling an adjustable fluid-filled lens assembly comprising biaxially tensioning an elastomeric membrane to a surface tension of greater than 180 N/m, typically greater than 1000 N/m; thermally conditioning the tensioned membrane, e.g., for one hour at a temperature of about 80&#xb0; C., to accelerate relaxation of the membrane; mounting the membrane to a peripheral support structure whilst maintaining the tension in the membrane; assembling the mounted membrane with one or more other components to form an enclosure with the membrane forming one wall of the enclosure; and thereafter filling the enclosure with a fluid. The membrane may be formed from an aromatic polyurethane, and the fluid may be a phenylated siloxane. In some embodiments, the membrane is able to hold a substantially constant surface tension of at least 180 N/m for a period of at least 12 months.

Adjustable fluid-filled lens assembly and method for assembling the same

Disclosed herein is an implantable accommodative IOL system for insertion into an eye of a patient, the system comprising: an optical element and a housing including an opaque frame. The optical element comprises an optical lens having variable optical power, and the opaque frame is circumferentially disposed around a periphery of the optical element.

Accommodating intraocular lens devices, systems, and methods using an opaque frame

The present invention relates to a method for the deformation and/or fragmentation of a cell, spore or virus, the method comprising: (i) bringing a liquid sample containing the cell, spore or virus into contact with a first surface of a vibratable plate having at least one aperture, and causing the plate to vibrate; and (ii) passing the sample of the cell, spore or virus through the at least one aperture in the vibrating plate so as to cause deformation and/or fragmentation of the cell, spore or virus. It also concerns a device for carrying out the method.

Method for deforming and/or fragmenting a cell, spore or virus with a vibrating plate

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Hertfordshire, United Kingdom

Rita Stella