Cosmosid Inc.

Research Corporation Technologies, Inc.

Canon U.S. Life Sciences, Inc.

Other

Research, Incorporated

Canon U.s.a., Inc.

Research Corporation Techniques, Inc.

Rita R Colwell

Dale B Bonar

John P Jakupciak

Steven L Coon

Ronald M Weiner

Gregory A Dale

Hiroshi Inoue

Ivor T Knight

Marianne Walsh

Boyd Thomas Livingston

Nur A Hasan

Jongsik Chun

Douglas M Brenner

David Jakupciak

Afzal Chowdhury

Marianne Walch

Franklin H Portugal

Anwarul Huq

Tom Cebula

Huai Li

At least one exemplary embodiment of the invention is directed to a molecular diagnostic device that comprises a cartridge configured to eject samples comprising genomic material into a microfluidic chip that comprises an amplification area, a detection area, and a matrix analysis area.

Method and molecular diagnostic device for detection, analysis and identification of genomic DNA

The present invention belongs to the field of genomics and nucleic acid sequencing. It involves a novel method of sequencing biological material and real-time probabilistic matching of short strings of sequencing information to identify all species present in said biological material. It is related to real-time probabilistic matching of sequence information, and more particular to comparing short strings of a plurality of sequences of single molecule nucleic acids, whether amplified or unamplied, whether chemically synthesized or physically interrogated, as fast as the sequence information is generated and in parallel with continuous sequence information generation or collection.

Method and system for genome identification

The present invention relates to systems and methods capable of characterizing populations of organisms within a sample. The characterization may utilize probabilistic matching of short strings of sequencing information to identify genomes from a reference genomic database to which the short strings belong. The characterization may include identification of the microbial community of the sample to the species and/or sub-species and/or strain level with their relative concentrations or abundance. In addition, the system and methods may enable rapid identification of organisms including both pathogens and commensals in clinical samples, and the identification may be achieved by a comparison of many (e.g., hundreds to millions) metagenomic fragments, which have been captured from a sample and sequenced, to many (e.g., millions or billions) of archived sequence information of genomes (i.e., reference genomic databases).

Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods

The present invention relates to detecting and distinguishing among bacteria that belong to the species, including, and; and detecting and distinguishingbacteria from. In particular, the invention includes provision of species-identifying and genus-identifying nucleotides of 16s rRNA or 16s rDNA from the above named species. Nucleic acid probe molecules capable of differentiating among these species and genera by hybridization, along with methods for their use for specific detection in clinical samples, food samples, environmental samples, and the like are also provided.

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The present invention relates to the discovery of a new bacteria of the genus Alteromonas which has been found to attract oyster larvae by the production of compounds involved in melanin synthesis. More specifically, the present invention contemplates a method for inducing the settlement and metamorphosis of Crassostrea virginica larvae by induction with certain metabolic substances produced by the present bacteria and its altered variants. Furthermore, the present invention is directed to other and derivative metabolic products which can be employed for their desired utility and application. In accordance with the present invention, it has been discovered that ammonia (NH.sub.3) initiates settlement and metamorphosis of the oyster larvae in the same manner as the natural phenomena.

Production and recovery of tyrosinase from melanin-synthesizing bacteria

Induction of settlement and metamorphosis in crassostrea virginica by

Induction of settlement and metamorphosis in Crassostrea virginica by

The present invention relates to the discovery of a new bacterium, alteromonas calwellii, which has been found to attract oyster larvae by the production of a compound involved in melanin synthesis. More specifically, the present invention contemplates a method for inducing the settlement and metamorphosis of Crassostrea virginica larvae by induction with certain metabolic substances produced by the present bacterium and its mutagenically altered variants. Furthermore, the present invention is directed to other and derivative metabolic products which can be employed for their desired utility and application.

Growing community of inventors

Bethesda, MD, United States of America

Rita R Colwell