Zoetis Services LLC

Other

Coley Pharmaceutical Group, Inc.

Zoetis LLC

Zoetis Belgium S.a

Risini Dhammika Weeratna

Paul Joseph Dominowski

James Richard Thompson

Richard Lee Krebs

Cedo Martin Bagi

Tedd Alan Childers

Mary Kathryn Olsen

Robert John Yancey, Jr

Shucheng Zhang

Ramasamy Mannar Mannan

Heather Lynn Davis

Ramasamy M Mannan

Sangita Mediratta

Robert John Yancey

Martin Cedo Bagi

Robert J Yancy

This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.

Adjuvant compositions

Described are vaccines having one or more antigens cholesterol and CpG. Aspects of the invention relate to the use of the vaccines of the invention for the treatment and/or prevention of human and animal disorders.

Vaccines comprising cholesterol and CpG as sole adjuvant-carrier molecules

The invention relates to immunostimulatory oligonucleotides and methods of using immunostimulatory oligonucleotides to induce an antigen-specific immune response. The invention further relates to a vaccine that comprises an immunostimulatory oligonucleotide and an antigen, and comprises a pharmaceutically acceptable carrier. The immunostimulatory oligonucleotides of the invention, in some embodiments, include one or more modified linkage(s).

Immunostimulatory oligonucleotides

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Ottawa, Canada

Risini Dhammika Weeratna