Other

Nascent Biotech, Inc.

Cancervax Corporation

Glassy, Mark C.

Gupta, Rishab K.

Rishab K Gupta

Donald L Morton

Mark C Glassy

David M Euhus

Jan H Wong

Compositions and methods related to antibodies or antibody fragments which are capable of crossing the blood brain barrier are provided.

Enhanced delivery of drugs to the brain

This invention provides the isolation and characterization of a tumor associated antigen which can be used for immunodiagnosis, immunoprognosis, and therapy of human cancer. The antigen is a protein molecule with a molecular weight of about 35 kD after reduction and separation by SDS-polyacrylamide gel electrophoresis. The antigen has been detected in serum of cancer patients.

35 kD tumor associated protein antigen: uses and methods of detection

The present invention describes Urinary Tumor Associated Antigen (UTAA), its isolation and use in diagnostic assays. In particular, UTAA has been identified in samples from cancer patients, in some cases as part of an immune complex of UTAA and UTAA-specific immunoglobulin. Isolated UTAA also may be formulated as a pharmaceutical for production of antibodies or as a vaccine.

Method of detection of urinary tumor associated antigen

Growing community of inventors

Van Nuys, CA, United States of America

Rishab K Gupta