Memorial Sloan Kettering Cancer Center

Ludwig Institute for Cancer Research Limited

Agenus Inc.

Rikke Baek Holmgaard

Gerd J Ritter

Taha Merghoub

Marc A Van Dijk

Nicholas Stuart Wilson

Jedd David Wolchok

David Schaer

David Adam Savitsky

Cornelia Anne Mundt

Roberta Zappasodi

Mark Arthur Findeis

Jean-Marie Cuillerot

Igor Proscurshim

Olga Shebanova

Provided are antibodies that specifically bind to CTLA-4 and/or PD-1 and antagonize CTLA-4 and/or PD-1 function. Also provided are pharmaceutical compositions and kits comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies either alone or in combination.

Antibodies and methods of use thereof

The instant disclosure provides antibodies that specifically bind to human PD-1 and antagonize PD-1 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Anti-PD-1 antibodies and methods of use thereof

Growing community of inventors

New York, NY, United States of America

Rikke Baek Holmgaard