Biovitrum Ab

Pharmacia Ab

Proximagen Limited

Rikard Emond

Edward Savory

Iain Simpson

Marianne Nilsson

Jerk Vallgårda

Guido Kurz

Tjeerd Barf

Lian Zhang

Erik Ringberg

Rolf A Johansson

Martin Haraldsson

Katarina Beierlein

Birger Sjoberg

Sofia Henriksson

Ian Vagberg

The present invention relates to compounds with the formula (I)  and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-&#x3b2;-hydroxysteroid dehydrogenase type 1 enzyme.

Inhibitors of 11-&#x3b2;-hydroxy steroid dehydrogenase type 1

The present invention relates to compounds with the formula (II) and also to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-&#x3b2;-hydroxysteroid dehydrogenase type 1 enzyme. 

Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

The present invention relates to compounds with the formula (I) 

The invention relates to novel compounds of Formula (I) wherein R,, R,, R,, R,, R,, R,, R,and Ar are as defined in claim,their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers. The compounds have anticholinergic activity, and the invention also relates to the compounds of Formula (I), the use of the compounds of Formula (I) for preparing anticholinergic drugs, the use of the compounds of Formula (I) for treating urinary tract incontinence, and methods for preparing the compounds of Formula (I).

Therapeutically active diarylpropylamines; their pharmaceutically acceptable salts; a method for their preparation and method for their use

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Saltsjöbaden, Sweden

Rikard Emond