C.c. Imex

Other

Richard T Chan

Winston Glenn Walker

Rita M Wong

Po Ling Cheng

Ramey K Chan

Robert G Becker

Min Kar Moi

Hidetaka Yamamura

Kelly C Chalmers

Jason In

An electrophoresis running tank assembly uses two opposed rows of LEDs to illuminate DNA-containing gel on a transparent tray positioned between the rows. A respective cylindrical lens is positioned horizontally between each row and a respective edge of the tray. The optical axis of the illumination light is midway between a bottom surface of the gel tray and a top surface of the gel.

Electrophoresis running tank assembly

The present invention discloses apparatuses and methods for the visualization of fluorophores in biological systems such as electrophoresis gels and cell cultures. Preferred embodiments of the apparatuses consists of a tray or tank having one or more light sources disposed to direct light through an electrophoresis gel disposed within the vessel such that the luminescence from fluorophores in the gel are easily visualized.

Illuminator for visualization of fluorophores

A combination construction for a tip and point ferrule of a billiard cue. The tip is manufactured from an epoxy resin reinforced glass fiber material that is used in the manufacturing of printed circuit boards. The material is formed into a rivet (mushroom) shape to allow the outer most part of the shaft that is shaped into a small cylindrical shaped object to be inserted into the cavity of a bush shaped point ferrule in order to connect with the small cylindrical object beneath the tip, and to allow the compression packing located between the tip and point ferrule to absorb the counter force of striking a billiard ball such that the tip and point ferrule are not damaged during impact.

Combination construction for tip and point ferrule of billiard cue

A gel cassette for electrophoresis includes opposed plastic plates holding a gel therebetween. An upper buffer tank can be adhered to one of the plates by double backed tape that is sandwiched between the tank and plate, thereby avoiding the use of a rubber sealing gasket between the tank and plate. As a result, the distance between the tank and the plate is kept constant. A buffer solution in the tank communicates with the gel. The cassette can then be placed in a lower buffer tank and an electric field applied to the buffer solutions to effect electrophoresis of DNA fragments that have been placed in the gel. In an alternate embodiment, a window is formed in one of the plastic plates to allow laser light to pass into the cassette and excite a fluorescent tag in the DNA. The fluorescence then passes back through the window for detection by a sensor, to automatically determine the DNA sequence of the sample in the gel in accordance with auto DNA sequencing principles. The window reduces and indeed eliminates absorption, interference, and/or reflection of the relatively weak fluorescent signal emitted by the DNA tag.

Gel cassette for electrophoresis

This invention provides a gel electrophoresis casting cassette for horizontal gel electrophoresis. The tray and lid of the cassette have locking means for securing the two parts to prevent damage to the slab gel and to create slab gels of uniform quality.

Growing community of inventors

La Jolla, CA, United States of America

Richard T Chan