Mallinckrodt, Inc.

Biomerieux, Inc.

Caire Inc.

Richard Scott Remes

Mark Robert Frye

Leonardo Shiki Toma

Stanley Michael Philipak

Lawrence E Guerra

Mark Joseph Fanning

James Clement Bishop

Ronnie J Robinson

Raymond E O'Bear

Michael Herron

Stan A Sanders

John I Izuchukwu

Brian Livingston

David Hertlein

Gary W Sommer

Timothy John Payne

Andrew J Scherer

Scott L Conway

Mike Ammerman

Ron Bergold

Anthony Valentino

Jeffrey S Dresow

Raymond O'bear

Michael A Herron

Gary Sommer

Michae A Herron

The present invention is directed to sample test cards having an increased sample well capacity for analyzing biological or other test samples. In one embodiment, the sample test cards of the present invention comprises a fluid channel network disposed in both the first surface and the second surface and connecting the fluid intake port to the sample wells, the fluid channel network comprising at least one distribution channels, a plurality of fill channels operatively connected to the at least one distribution channel, a plurality of through-channels operatively connected to one or more of the fill channels and a plurality of horizontally orientated fill ports operatively connecting the fill channels to the sample wells. In another embodiment, the sample test cards may comprise a fluid channel network comprising a first distribution channel disposed on a first surface, the first distribution channel comprising a fluid flow path from an fluid intake port to a plurality of second distribution channels or diffusion channels, wherein the second distribution channel or diffusion channels further comprise a plurality of diffusion barriers or 'islands' operable to interrupt fluid flow between opposing sample wells, and wherein the second distribution channels or diffusion channels are operatively connected to the sample wells by a plurality of fill channels. The test card of this invention may comprise from 80 to 140 individual sample wells, for example, in a test card sample test cards of the present invention have a generally rectangular shape sample test card having dimensions of from about 90 to about 95 mm in width, from about 55 to about 60 mm in height and from about 4 to about 5 mm in thickness.

Sample test cards

A method and automated apparatus for rapid non-invasive detection of a microbial agent in a test sample is described herein. The apparatus may include one or more means for automated loading, automated transfer and/or automated unloading of a specimen container. The apparatus also includes a detection system for receiving a detection container, e.g., container or vial, containing a biological sample and culture media. The detection system may also include one or more heated sources, holding structures or racks, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent therein. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system.

Automated microbial detection apparatus

The present invention is directed to a method and automated loading mechanism for loading an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system.

Automated loading mechanism for microbial detection apparatus

The present invention is directed to sample test cards having an increased sample well capacity for analyzing biological or other test samples. In one embodiment, the sample test cards of the present invention comprises a fluid channel network disposed in both the first surface and the second surface and connecting the fluid intake port to the sample wells, the fluid channel network comprising at least one distribution channels, a plurality of fill channels operatively connected to the at least one distribution channel, a plurality of through-channels operatively connected to one or more of the fill channels and a plurality of horizontally orientated fill ports operatively connecting the fill channels to the sample wells.

A portable liquid oxygen (LOX) storage/delivery apparatus is provided, including an insulated (LOX) container having an interior, a bottom portion and a sidewall, the sidewall including a first side portion and a second side portion, both extending between the top portion and the bottom portion, and a port system in communication with the interior of the container for charging the container and for withdrawing LOX and gaseous oxygen from the container. The gaseous oxygen is withdrawn from the container through a first outlet and LOX is withdrawn from the container through a second outlet. Gaseous oxygen can be withdrawn from the container through the first outlet and LOX can be withdrawn from the container through the second outlet when the container is positioned in a first orientation with the sidewall vertically oriented, as well as when the container is positioned in a second orientation with the second side portion oriented downwardly and with the first side portion oriented upwardly and overlying the second side portion, and any position in between.

Portable liquid oxygen unit with multiple operational orientations

A portable liquid oxygen (LOX) storage/delivery apparatus is provided, including an insulated (LOX) container having an interior, a top portion, a bottom portion and a sidewall, the sidewall including a first side portion and a second side portion, both extending between the top portion of the bottom portion, and a port system in communication with the interior of the container for charging the container and for withdrawing LOX and gaseous oxygen from the container.

A portable liquid oxygen (LOX) storage/delivery apparatus is provided, including an insulated LOX container having an interior, a top portion, bottom portion, and sidewall, the sidewall including a first and second side portion, both extending between the top and bottom portion, and a port system in communication with the interior for charging the container and for withdrawing LOX and gaseous oxygen. The gaseous oxygen is withdrawn from the container through a first outlet and LOX is withdrawn from the container through a second outlet when the container is positioned in a first orientation with the sidewall vertically oriented, as well as when the container is positioned in a second orientation with the second side portion oriented downwardly and with the first side portion upwardly and overlying the second side portion, and any position in between.

A wearable storage system for pressurized fluid includes a pressure vessel formed from a plurality of polymeric hollow chamber having either en ellipsoidal or spherical shape and interconnected by a plurality of relatively narrow conduit sections disposed between consecutive ones of the chambers. The pressure vessel includes a reinforcing filament wrapped around the interconnected chambers and interconnecting conduit sections to limit radial expansion of the chambers and conduit sections when filled with a fluid under pressure. The container system further includes a fluid transfer control system attached to the pressure vessel for controlling fluid flow into and out of the pressure vessel. A gas delivery mechanism for delivering gas stored in the pressure vessel to the patient in a controlled manner is connected to the fluid transfer control system. The pressure vessel and the fluid transfer control system are incorporated into a wearable garment to provide an ambulatory supply of gas for the patient.

Wearable storage system for pressurized fluids

A fluid transfer control valve is connected to a pressure vessel formed from a plurality of hollow, polymeric chambers interconnected by polymeric conduit sections disposed between adjacent ones of the chambers. The valve includes a valve body and a pressure relief mechanism attached to the body. The pressure relief mechanism is operative to release pressure from the pressure vessel when the pressure within the vessel exceeds a predetermined maximum pressure. In a preferred embodiment, the relief mechanism comprises a rupture disk. The pressure relief valve may also include a filter element disposed along a fluid flow path defined within the valve body and/or a restrictive flow path for reducing the pressure of fluid flowing through the valve body.

Fluid control valve for pressure vessel

Portable gas dispenser

Combined storage and delivery container system for a breathable gas

A cryogenic liquid delivery system includes a storage tank holding a quantity of a cryogenic liquid such as liquid oxygen and a vapor space. A compound, two-part dip tube includes an inner liquid delivery tube and an outer tube which is sealed to allow liquid cryogen to be delivered to a vaporizer only via the liquid delivery tube. The vaporizer communicates with the vapor space in the tank via an aperture in the outer tube, above the level of the liquid cryogen and the seal.

Growing community of inventors

Chesterfield, MO, United States of America

Richard Scott Remes