Edwards Lifesciences Corporation

Covidien LP

Baxter International Inc.

Micardia Corporation

Sfb Development LLC

Richard S Rhee

Samuel M Shaolian

Richard S Kusleika

Mark Philip Ashby

Stefan G Schreck

Earl Frederick Bardsley

Vincent Divino

Madhur Arunrao Kadam

Patrick M McCarthy

Julie Kulak

Delos M Cosgrove, Iii

Keith E Myers

Shahram Moaddeb

Alain F Carpentier

Gaurav Girdhar

Hung Ly Lam

Steven F Bolling

John Wainwright

Emanuel Shaoulian

Diana Nguyen-Thien-Nhon

Can B Hu

Ujwal Jalgaonkar

Teresa Ruvalcaba

Steven R Anderson

Khoa Vu

Jerry L Jackman

Ramon Carrillo

Than Nguyen

Vince Divino

Minh T Ma

Ross Bartholomew

Ashok Nageswaran

Hoai Nguyen

Kokou A Amefia

William J Recktenwald

Robert J Todd

Rich Kusleika

Victor S Packham

Seik Oh

Charles R Weyrauch

Diana Nguyen

Jane Li

Delos M Cosgrove

John James McIntyre

Junwei Li

Salvador Marquez

Syamala Rani Pulugurtha

Eric Mintz

Andyanhdzung Huynh

Kenneth Brown

Stephen Sosnowski

Erik Skillrud

Carl A Swindle

Robert W Frater

Gopan Patel

George X Guo

Claudio Argento

Norma L Lowe

Lisa Deseran

Patrick M Mccarthy

Steven F M D Bolling

Seteven C Anderson

Treatment of an aneurysm or other vascular defect can be facilitated or enhanced by an implant delivered with a thermally activated detachment system. A delivery system can include an implant with a proximal portion that defines a port. A pusher device can include arms extending distally from a junction of the pusher device and through the port, with distal sections of the arms disposed within the implant. The arms can, at a certain temperature, transition from engagement with the implant to a shape that facilitates release of the implant. Additionally or alternatively, a coil can engage an outer surface of the implant at the proximal portion and transition to a shape that facilitates release of the implant.

Implant detachment with thermal activation

A system for treatment of an aneurysm includes an intrasaccular device that can be delivered using a catheter. The device can include at least one expandable structure adapted to transition from a compressed configuration to an expanded configuration when released into the aneurysm. The expandable structure can have a specific shape or porosity. Multiple expandable structures can also be used, in which case each of the expandable structures can have a unique shape or porosity profile. The morphology of the aneurysm and orientation of any connecting arteries can determine the type, size, shape, number, and porosity profile of the expandable structure used in treating the aneurysm.

Occlusive devices

An aneurysm embolization device can include a body having a single, continuous piece of material that is shape set into a plurality of distinct structural components. For example, the device can have an expandable component and an atraumatic tip portion extending therefrom. Further, the tip portion can be configured to enable the device to be implanted within the aneurysm while tending to mitigate risk of puncturing the aneurysm dome or otherwise assist in framing the aneurysm in advance of placement of additional embolic material.

Occlusive device

Delivery and detachment of an implant can be enhanced by a retraction mechanism to secure portions of a delivery wire within an interior space of the implant. A delivery system can include an implant having a proximal end portion. A delivery wire can include (i) a detachment zone proximal to the proximal end portion and (ii) a distal region distal to the proximal end portion. An expansion member can be located between the proximal end portion and the distal region of the delivery wire. The expansion member can be biased to move the distal region of the delivery wire distally away from the proximal end portion when severed at the detachment zone.

Electrolytic detachment for implantable devices

An implant can include a single- or dual-layer braided body having a variable porosity. In a dual-layer body, first and second longitudinal sections, having respective first and second porosities, can be overlapped such that the first and second porosities overlap each other. The dual-layer construction can cumulatively provide a third porosity at a distal portion and a fourth porosity at a proximal portion. The third and fourth porosities can each be greater than each of the first and second porosities.

Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity via an elongated shaft and transforming a shape of the occlusive member within the cavity. The method may include introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall. In some embodiments, the elongated shaft is detachably coupled to a distal portion of the occlusive member.

Devices, systems, and methods for treatment of intracranial aneurysms

An occlusive device for occluding a target area can include an elongate member having opposing first and second side edges extending longitudinally along the member and a member width. The member can have a collapsed configuration in which the first and second side edges are curled toward each other about a longitudinal axis of the member. Further the member can have an expanded configuration in which the member form a series of loops and the first and second side edges uncurl to be spaced apart from each other.

Embolic medical devices

An implant can include a frame and a mesh component coupled to the frame. The mesh component can define a first porosity, and the frame can define a frame porosity. The combined porosity of the mesh component and the frame can restrict blood flow into the implant.

Systems and devices for endovascular treatment of intracranial aneurysms are described. Various configurations of coiled implants may be used as stenting devices or aneurysm coils. The implants include one or more filaments wound about a longitudinal axis to form a generally tubular shape. Lateral flexibility of the implants may be manipulated by, for example, adjusting a pitch between adjacent filaments, using different materials for the filaments, employing different filament cross-sectional shapes, grouping filaments into pluralities of varying flexibilities, and nesting inner coils within outer coils.

Aneurysm treatment coils

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Diamond Bar, CA, United States of America

Richard S Rhee