Genaissance Pharmaceuticals, Inc.

Pgxhealth, LLC

Richard S Judson

J Claiborne Stephens

Andreas Windemuth

R Rex Denton

Krishnan Nandabalan

Stephen Bryant Liggett

Nadine Cohen

Jeroen Aerssens

Gualberto Ruaño

Bradley Dain

Vural Ozdemir

Carol R Reed

Maria Athanasiou

Chuanbo Xu

Catherine B Stack

Carlos Brain

Connie M Drysdale

Haplotypes in the CDK5 gene associated with cognitive response to galantamine treatment are disclosed. Compositions and methods for detecting and using these CDK5 haplotypes in a variety of clinical applications are disclosed. Such applications include articles of manufacture comprising galantamine or derivatives thereof that are approved for treating patients having one of these CDK5 haplotypes, methods and kits for predicting the response of an individual to galantamine based upon his/her haplotype profile, and methods for treating Alzheimer's patients based upon their haplotype profile.

CDK5 genetic markers associated with galantamine response

Methods, computer program(s) and database(s) to analyze and make use of gene haplotype information. These include methods, program, and database to find and measure the frequency of haplotypes in the general population; methods, program, and database to find correlation's between an individual's haplotypes or genotypes and a clinical outcome; methods, program, and database to predict an individual's haplotypes from the individual's genotype for a gene; and methods, program, and database to predict an individual's clinical response to a treatment based on the individual's genotype or haplotype.

Methods for obtaining and using haplotype data

A method of ensuring the security of data from a medical test includes providing the patient with a medical data card issued by a secure information provider, and having a unique patient identification number (PID), a public key encryption private key, and public key encryption public key (Key). The method further includes a first test request card having an encrypted identification of the patient and the test, a health care provider code, Key, and the test type that accompanies the patient's test specimen to the secure information provider, a second test request card bearing an encryption of the PID and the test type to forward with the patient's specimen to a testing laboratory; a first test results card bearing an encryption of the PID and the results; and a second test results card that may be read in conjunction with the patient's medical data card.

Methods and apparatus for ensuring the privacy and security of personal medical information

Genotypes and haplotypes for thirteen polymorphic sites in the &bgr; -adrenergic receptor (&bgr; AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr; AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.

Association of &bgr;2-adrenergic receptor haplotypes with drug response

Growing community of inventors

Guilford, CT, United States of America

Richard S Judson