Best Theratronics Ltd.

Richard Ray Johnson

William Z Gelbart

Glenn McRae

Brian Abeysekera

Lidia Matei

Glenn Mcrae

A process for the separation ofTc from molybdenum targets is described. The method for separation ofTc isotope from molybdenum targets includes: i) providing an initial multicomponent mixture of elements, the mixture containingTc; ii) dissolving the multicomponent mixture of elements with an oxidizing agent to oxidize the mixture of elements; iii) heating the mixture of elements at a temperature sufficiently high enough to sublimate a vaporized compound containingTc; iv) condensing the vaporized compound containingTc to form a reaction product; v) adding a base to the condensed reaction product to dissolve theTc containing reaction product to form sodium pertechnetate (NaTcO); and vii) purifying the crude solution of sodium pertechnetate NaTcOusing column chromatography to provide theTc isotope as a radiochemical compound.

System and method for metallic isotope separation by a combined thermal-vacuum distillation process

Apparatuses and methods for production of molybdenum targets, and the formed molybdenum targets, used to produce Tc-99m are described. The target includes a copper support plate having a front face and a back face. The copper support plate desirably has dimensions of thickness of about 2.8 mm, a length of about 65 mm and a width of about 30 mm; and the copper support plate desirably has either a circular or an elliptical cavity centrally formed therein by pressing molybdenum powder into the front face with a depth of about 200-400 microns. Also, the copper support plate includes cooling channels dispensed at the back face; wherein the copper support plate is water cooled by a flow of water during irradiation by a proton beam. Molybdenum powder is embedded and compressed onto the cavity of the copper support plate thereby creating a thin layer of molybdenum onto the copper support plate.

Target, apparatus and process for the manufacture of molybdenum-100 targets

A process for the separation ofTc from molybdenum targets is described. The method for separation ofTc isotope from molybdenum targets includes: i) providing an initial multicomponent mixture of elements, the mixture containingTc; ii) dissolving the multicomponent mixture of elements with an oxidizing agent to oxidize the mixture of elements; iii) heating the mixture of elements at a temperature sufficiently high enough to sublimate a vaporized compound containingTc; iv) condensing the vaporized compound containingTc to form a reaction product; v) adding a base to the condensed reaction product to dissolve theTc containing reaction product to form sodium pertechnetate (NaTcO); and vii) purifying the crude solution of sodium pertechnetate NaTc04 using column chromatography to provide theTc isotope as a radiochemical compound.

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Richard Ray Johnson