Signature Systems LLC

Other

Voc Health, Inc.

Richard Postrel

Zallascht Postrel

Raymond Catania

Christine Bralich

Ian Hunter

Kenan Dunton

An apparatus and method for determining the presence of a disease by analyzing a specimen by providing a vial partially containing the specimen and partially containing a headspace above the specimen, injecting an inert gas into the specimen in the vial to cause bubbling of the gas throughout at least a portion of the specimen such that the gas mixes with volatile organic compounds (VOCs) present in the specimen to create a VOC/gas mixture that is released into the headspace, collecting the VOC/gas mixture from the headspace in the vial, supplying the VOC/gas mixture to a chamber within the apparatus, causing the VOC/gas mixture to pass over a sensor array in proximity to the chamber, the sensor array generating an electrical signal as a function of VOCs detected in the VOC/gas mixture, and processing the electrical signal to determine the presence of a disease in the specimen.

Apparatus and method for measuring volatile organic compounds in a specimen to detect the presence of diseases

A drone traffic management system comprising a computer comprising memory means for storing origin coordinates indicating an origin location of a drone, destination coordinates indicating a destination of the drone, and traffic management factors located between the origin location of the drone and the destination of the drone; and processing means for controlling the flight of a drone. This is accomplished by calculating a flight path for the drone to fly automatically from the origin location to the destination location without manual intervention, sending the flight path to the drone, receiving location data of the drone as it travels from the origin location to the destination, re-calculating the flight path of the drone as a function of the traffic management factors and the location data of the drone, and sending the re-calculated flight path to the drone.

System and method for automated traffic management of intelligent unmanned aerial vehicles

A toddler walker having a body comprising a bottom panel, and a front panel, a rear panel, and a pair of side panels attached to the bottom panel so as to form an open box; at least four wheel assemblies, each comprising a wheel rotatably affixed to the body so that when the wheels rotate the body moves via the wheels along a surface; a handlebar assembly comprising a handlebar, means for adjusting the handlebar to a desired vertical position, and a pair of leg channels pivotally connected to the side panels to enable a toddler to grasp said handlebar assembly when located behind the body and direct movement of the body along the surface; and a display device assembly pivotally connected to the handlebar assembly and comprising means for removably attaching a display device further comprising means for adjusting the height of the display device.

Toddler walker with interactive display device having multiple adjustment modes

The present invention provides a process and method for the early detection and diagnosis of disease by reading and decoding volatile organic compounds (VOCs) for signatures associated with a specific disease. Urine is available as a diagnostic sample providing its off gas with VOCs for rapid screening from its outset, each disease begins producing its own unique set of volatile organic compounds. For many diseases, this early-stage detection may be many months or years before noticeable symptoms. The VOC emissions when analyzed, result in a 'signature' that identifies and distinguishes the developing, or at later stages, the developed disease. The device assays non-invasively obtained biosamples in real-time to output a VOC based signature that, when correlated with data in a disease signature library, identifies one or more diseases associated with the sample.

Advanced cancer detection in urine

Disclosed is a device for testing or screening individuals for symptoms of disease, exposure to restricted chemical or bio-hazards. The device may be configured as a compact box or tubular assay chamber. A sluice or walkway is provided for assaying moving animals. The present device assays volatile compounds, especially volatile organic compounds (VOCs) emitting from a subject individual. Different VOCs are produced as metabolic activity changes as an individual addresses a pathogenic, chemical or biological stress or progresses through normal biologic cycles such as sleepwake, seasonal, fertility, etc. The system is especially advantageous for timing breeding events and apportioning feed for desired levels of milk production and calf health. Nanosensor elements within the device provide assessment of multiple VOCs to a system with integrated analysis capacities that rapidly compares instant data to a developed database. This comparison allows rapid assessment of metabolic or health status and potential risks the individual or offspring of the individual may face.

Volatile organic compound bio-scanning system for food chain safety and security

The present invention provides an improved system, device, and method for determining a comprehensive state of health in real time using non-invasive patient testing. The invention characterizes disease and other states of health by simultaneously assaying both liquid and gas in a sample or samples. During metabolism, the body performs a large variety of biochemical reactions. Reaction products, reaction by-products, and breakdown products are transported by the circulatory system throughout the body. Many of these molecular products are labile and volatilize into gases from bodily liquids. In gas form, these compounds appear as volatile organic compounds (VOCs).

Comprehensive health status by simultaneously reading volatile and non-volatile compounds

The present invention discloses a system and method for preparing and delivering various precursor compositions as a replacement therapy for testosterone and other hormone deficiencies that naturally occur with aging in humans and other mammals. Precursor compositions are selected and designed for the purpose of formulating non-toxic therapeutic hormone supplement for oral consumption. The invention features low dose continuous supplementation to be incorporated with daily meals. The process of the present invention delivers an orally ingested substance, e.g., a food, supplement, etc., that contains an anti-aging formulation comprising a hormone precursor (prohormone) that is absorbed by the digestive system and secreted into the bloodstream with a second substance to facilitate its ingestion, absorption and delivery to the body's tissues.

Anti-aging therapy for humans and other mammals

A portable display device assembly suitable for use with a separate apparatus such as a toddler walker, cart, wagon or similar apparatus and which is adjustable to suit the needs of the user. The portable display device assembly has means for holding a display device, which includes a display device support panel and a display device support rail slidingly engaged with the display device support panel such that the height of the display device support rail may be raised or lowered with respect to the display device support panel. There is also a means for pivoting the display device support panel and means for attaching the means for holding a display device to a separate apparatus.

Adjustable display device assembly

The present invention discloses a system and method for increasing the lifespan and quality of life of human beings and other mammals. This discloses methods for preparing and delivering various health and longevity compositions. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation, misting, nasal spray, suppository, etc. An existing compound known to have capacity for life extending potential, rapamycin, is combined with a non-toxic therapeutic anabolic hormone, e.g., DHEA, and cannabidiol (CBD) to enable absorption and effect. These three compounds work together to dramatically improve both the quality of life in aging humans and other mammals as well as extending the life of humans potentially up to 120 healthy years. One preferred embodiment provides a method for continuous low dose supplementation, e.g., incorporated in or with a daily meal. This invention not only resolves the issue of anti-aging of higher life forms, without toxicity, but provides for an improved method for absorption.

Life extension for humans and other mammals

The present invention discloses a system and method for improving the quality of life in canines and other domesticated animals. As animals age testosterone and other supportive hormones diminish causing reduced activity, a lack of mobility, decreased bone density, and general well-being. Precursor compositions are selected and designed for the purpose of formulating non-toxic therapeutic hormone supplements for oral consumption. The process and method of this invention is comprised of therapies produced from two or more selected non-toxic prohormones that combine during digestion and delivered through a chewable and edible gummy treat. As such there is no requirement for changing the subject's current diet. The present invention features a continuous low dose supplementation to be incorporated daily whereby dosages are correlated according to the subject's age, weight, sex, and breed. The beneficial results of the present invention are achieved through the absorption of the prohormones in the composition into the bloodstream effecting delivery to all cells including those specific cells where the conversion enzymes are activated by the organism's needs. The delivery and transport of inactive prohormones minimizes liver toxicity since the precursors are carried through the hepatic portal system to and through the liver and into general circulation in inactive forms.

Anti-aging therapy for canines and other domesticated animals

The present invention discloses a system and method for preparing and delivering various health and longevity compositions. This invention is designed to improve the quality of life and lifespan of mammals. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation; misting; nasal spray; intravenous, IM, and/or sub-cutaneous, injection; suppository; etc. A non-toxic therapeutic anabolic hormone replenishment is combined with rapamycin and cannabidiol. The three compounds work together to improve quality of life and healthy lifespan. Preferred additional included supplements may include metformin, growth hormone, and/or supplemented minerals. A preferred embodiment features low dose continuous supplementation, e.g., to be incorporated with a daily meal. The process of the present invention delivers an orally ingested substance, e.g., a snack, a human food supplement, an animal treat, etc., that contains the active compounds to be absorbed by the digestive system or delivered into the bloodstream.

Extending human life with non-invasive mTOR inhibitor compositions

This invention reverses male pattern baldness by shocking dormant hair follicles out of their androgen induced hibernation phase back to the active hair-growing anagenic phase. The invention integrates two functions: 1) It blocks synthesis of compounds holding the follicles in the telogenic/hibernating phase and 2) It stimulates synthesis of compounds animating the hair-growing/anagenic phase in the follicular activity cycle. One preferred embodiment comprises an enzyme inhibitor blocking the conversion of testosterone to dihydrotestosterone (DHT), a flavonoid simultaneously increasing synthesis of prostaglandins alternative to prostaglandin D, and a selected cannabinoid compound stimulating restore the hair follicle to its normal growth cycle. This novel trimodal therapy restores the hair follicles to their normal cycling processes and maintains these restorative properties so long as this rebalance in maintained.

Reversing baldness through cannabinoid receptor activation

The present invention discloses a system and method for preparing and delivering various precursor compositions as a replacement therapy for testosterone and other hormone deficiencies that naturally occur with aging in canines and other domesticated animals. Precursor compositions are selected and designed for the purpose of formulating non-toxic therapeutic hormone supplement for oral consumption. The invention features low dose continuous supplementation to be incorporated with daily meals. The process of the present invention delivers an orally ingested substance, e.g., a food, supplement, treat, etc., that contains an anti-aging formulation comprising a hormone precursor (prohormone) that is absorbed by the digestive system and secreted into the bloodstream with a second substance to facitate its ingestion, absorption and delivery to the body's tissues.

The present invention provides a process and method for the early detection and diagnosis of disease by reading and decoding volatile organic compounds (VOCs) for signatures associated with a specific disease. From its outset, each disease begins producing its own unique set of volatile organic compounds. For many diseases, this early-stage detection may be many months or years before noticeable symptoms. The VOC emissions when analyzed, result in a 'signature' that identifies and distinguishes the developing, or at later stages, the developed disease. The device assays non-invasively obtained biosamples in real-time to output a VOC based signature that, when correlated with data in a disease signature library, identifies one or more diseases associated with the sample.

Instant early stage disease detection by decoding organic compound signatures

The present invention provides a device and process that rapidly assesses volatile organic compounds (VOCs) present in a gaseous state by reading gas emitted through a subject's skin into the ambient surroundings. The device delivers rapid high-sensitivity capture, classification and pattern recognition to identify a unique VOC profile derived from that bio-sample. A flexible probe module can be appropriately configured with attachments to collect gases from the air surrounding any person, any area enclosed or proximal to a potential VOC source, and/or in clinical applications, near any skin surface, from zones or areas within or immediate adjacent to a body orifice such as nasal passage, otic canal, mouth, armpit, vagina, urethra, navel, anus, vagina, scalp, torso, palm, foot, etc. The device thus provides a practical screening device for clearing persons of interest, e.g., in a waiting room, planning to enter a room or building, a client seeking a personal meeting, etc., and/or providing a handyman, health care worker, or other service provider, a means of assurance when entering a place of service.

Growing community of inventors

Miami Beach, FL, United States of America

Richard Postrel