American Home Products Corporation

Richard P Carlson

Alan J Lewis

Peter H Wei

Richard L Fenichel

Milton Wolf

Horace Fletcher, 3rd

This invention discloses 5-(4-hydroxyphenyl)-4-phenyl-2-oxazolepropanoic acid, 4-(4-hydroxyphenyl-5-phenyl-2-oxazolepropanoic acid and pharmaceutically acceptable salts thereof as antiinflammatory agents, pharmaceutical compositions thereof and methods for their use.

Hydroxy substituted 4,5-diphenyl-2-oxazole propanoic acid

There are disclosed compounds having the formula ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, trifluoromethyl or halo;

Phenylpyrazolidine acetic acid derivatives

A method of modulating the immune response in mammals by administering thereto compounds having the general formula: ##STR1## where R is hydrogen or alkyl of 1-4 carbon atoms, R.sup.1 is hydrogen or an alkyl of 1-4 carbon atoms and pharmaceutically acceptable salts thereof.

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Lansdale, PA, United States of America

Richard P Carlson