Stryker Corporation

Stryker European Holdings I LLC

Edwards Lifesciences Corporation

Embolx, Inc.

Stryker Nv Operations Limited

Boston Scientific Scimed, Inc.

Medtronic, Inc.

Stryker European Operations Holdings LLC

Cardiovascular Concepts, Inc.

Other

Medtronic Ave, Inc.

Vascular Architects, Inc.

Richard O Murphy

Hancun Chen

Roman Turovskiy

Lantao Guo

Tri D Tran

Clifford Teoh

Kim D Nguyen

Hanh Ho

My Doan

Timothy J Wood

Jay Alan Lenker

Harold F Carrison

Robert M Abrams

Tracy D Maahs

Bruce S Addis

Jimmy D Dao

Michael P Wallace

William M Ambrisco

Timothy Odell

Michael A Evans

Michael Scott Williams

Gwendolyn A Watanabe

Timothy J Ryan

Kirsten Freislinger

Justin Vo

Yue-Teh Jang

Richard S Lilly

Steve Kim

Rodney A White

Thomas J Fogarty

Kamal Ramzipoor

Stephen Christopher Porter

Like Que

Christopher K Zarins

Brian A Glynn

Peter Thornton, Jr

Scott Anthony McGill

Andrew Huffmaster

Brian J Cox

Nestor Aganon

Russell B Ford

Jobert P Balceta

Kevin Hahnen

Charles Daly

Christopher Zarins

William S Henry

Hanh H Duong

Lorraine Mangosong Martinez

Lilibeth S Camins

Franciscus Laureus Moll

Menno Kalmann

Kenneth Mollenauer

Hughie Devaney

Shana B Castelli

A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Vaso-occlusive device delivery system

A vaso-occlusive treatment system includes a delivery assembly; and a vaso-occlusive device detachably coupled to the delivery assembly by a delivery assembly junction. The vaso-occlusive device includes a braided portion formed out of one or more composite wires, a coiled portion coupled to the braided portion, and an intra-device junction coupling the braided portion to the coiled portion. Each composite wire includes a core made from a core metallic material, and an external layer made from an external metallic material different from the core metallic material. One of the core and the external layer has a greater radiopacity and a lesser stiffness, respectively, than the other one of the core and the external layer.

Vaso-occlusive device and delivery assembly

A vaso-occlusive device includes an inner coil made from inner coil wire having a first diameter and formed from a first material, and an outer coil disposed at least partially around the inner coil and made from outer coil wire having a second diameter and formed from a second material. The inner coil has a first pitch and the outer coil has a second pitch. The first diameter, material, and pitch are different from the second diameter, material, and pitch, respectively. In some embodiments, the second diameter is less than the first diameter, the second material is softer than the first material, and the second pitch is more open than the first pitch. In some embodiments, the inner coil extends proximally beyond the outer coil. In one embodiment, a vaso-occlusive device includes an outer coil defining a lumen and an inner coil disposed at least partially in the lumen, wherein the vaso-occlusive device also includes an intermediate layer disposed between the inner coil and the outer coil, wherein the intermediate layer includes a biocompatible metal or a biocompatible, swellable polymer. The vaso-occlusive device may also include a biodegradable coating disposed on the outer surface of the inner coil. In one embodiment, a vaso-occlusive device includes an outer coil and a plurality of inner coils of increasing size each disposed immediately inside of the outer coil or one of the inner coils.

Vaso-occlusive device

A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

A device for delivering an occlusive element includes an elongate sheath having a lumen therein. An elongate core member is disposed within the lumen and is formed from a proximal portion and distal portion connected via a joint. The distal portion of the elongate member includes a severable junction secured to the occlusive element. A marker coil is coaxially arranged around the distal portion of the elongate core member and is partially disposed inside the sheath lumen. A coil member is coaxially arranged around the distal portion of the elongate core member and coaxially arranged around at least a portion of the marker coil extending outside the lumen of the sheath. The coil member is secured at a distal end thereof to the distal portion of the elongate core member. The device resists axial compression while allowing for radial bending.

Vaso-occlusive delivery device with kink resistant, flexible distal end

A vaso-occlusive device delivery assembly includes a pusher assembly having a proximal end, a distal end, and a pusher lumen extending therebetween; a vaso-occlusive device; and a tubular member mechanically connecting the pusher assembly to the vaso-occlusive device, the tubular member having a proximal end, a distal end, a tube lumen extending therebetween, and a detach zone, wherein the proximal end of the tubular member extends into the pusher assembly lumen at the distal end of the pusher assembly. A heat generating member is disposed in the tube lumen, such that, when activated, the heat generating member generates heat that melts or otherwise thermally degrades the tubular member at the detach zone, thereby detaching the vaso-occlusive device from the pusher assembly.

A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.

Delivery wire for occlusive device delivery system

A vaso-occlusive device includes a first coil made from a first substantially non-expansile material, and a second coil at least partially co-wound with the first coil and made from a second expansile material. The second coil has a contracted state and an expanded state, in which the second coil expands radially and/or longitudinally. The vaso-occlusive device has increased stiffness when the second coil is in its expanded state.

Vaso-occlusive devices with in-situ stiffening

A vaso-occlusive delivery system includes a vaso-occlusive coil, delivery wire assembly, and a link. The vaso-occlusive coil defines a coil lumen and has first and second coil windings defining a coil opening therebetween. The delivery wire assembly defines a delivery wire lumen, and includes an electrolytic detachment zone, a delivery wire conduit, and a delivery wire attached to the delivery wire conduit and extending through the delivery wire lumen distal of the delivery wire conduit. The link defines a link lumen and has link body including a proximal end of the link body defines an link opening in communication with the link lumen and a distal end of the link body includes a link detent extending radially from the link body, through the coil opening, securing the link body and the delivery wire assembly to the vaso-occlusive coil.

Growing community of inventors

Mountain View, CA, United States of America

Richard O Murphy