System of Systems Analytics, Inc.

Presympto, Inc.

Richard O Cliff

Giora Z Feuerstein

Robert W Flower

Evgenia G Matveeva

Methods of detecting A&#x3b2; oligomers, such as may be present in a biological sample are described. The methods include detection using flow cytometry, detection using synthetic A&#x3b2; oligomers and/or in vitro methods detecting A&#x3b2; oligomers associated with cells.

Methods for detecting A&#x3b2; oligomers

Described are methods for the detection, in the eye of an individual, of protein aggregates or other misfolded proteins associated with disease using peptide or peptide mimic probes that preferentially associate with the protein aggregates or misfolded proteins, which can be accomplished non-invasively.

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Fairfax Station, VA, United States of America

Richard O Cliff