Relia Diagnostic Systems, LLC

Praxsys Biosystems, Inc.

Other

Chiron Corporation

Richard M Thayer

Alan J Polito

Robert K Dinello

George H Sierra

Alan C Phillips

Stuart K Neubarth

Dennis Nixon

Henry J Wieck

Dino Dina

Steven Rosenberg

Paul A Luciw

Nancy L Haigwood

Barbara S Chapman

George Konewal

Edgar J Tooley

Stuart Neubarth

An embodiment of the present invention provides a-method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.

Method and apparatus for performing a lateral flow assay

An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.

A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample addition zone, at least one of the test zones including a first analyte binding agent immobilized therein which is capable of binding to the analyte to be detected; and a terminal sample flow zone distal to the one or more test zones, the absorbent zone being positioned relative to the sample addition zone and having an absorption capacity relative to the other zones of the test strip such that a distal diffusion front of a sample added to the sample addition zone diffuses from the sample addition zone to a distal diffusion point within the terminal sample flow zone and then reverses direction and diffuses proximal relative to the one or more test zones.

Bidirectional lateral flow test strip and method

Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.

Vector for expression of a polypeptide in a mammalian cell

An aromatic alarm system for awakening a user to a pleasant smell at a pre-selected time comprising, in combination an electronic processor couplable to a source of power adapted to provide electric power and controls to the system; an optical display operatively coupled to the processor to display a time of day and a starting time, the optical display having associated operator variable controls to change the time of day and starting time; and an atomizer, a housing supporting the atomizer, the housing also supporting the processor, the atomizer including a reservoir of fluid to be atomized, an outlet orifice for dispensing atomized fluid, tubing coupling the outlet orifice and reservoir, a pump coupled to the tubing to convey fluid from the reservoir to the outlet orifice and convert it from the liquid state into the atomized state, a motor with an operator controlled variable resistor to operate the pump at a pre-selected intensity, an operator controlled on/off switch to energize the motor to allow activation of the motor and pump as a function of the starting time of the optical display as selected by the operator.

Aromatic alarm clock system

Growing community of inventors

Alamo, CA, United States of America

Richard M Thayer