Hoechst Aktiengesellschaft

Richard Leeb

Willi Stammberger

Manfred Radau

Martin Bickel

Rolf Geiger

Walter Petri

Werner Fulberth

Werner Fulbreth

Rainer J Helbig

Stabilized medicinal substances, a process for the preparation thereof, and stable medicinal formulations Stabilized compounds of the formula I ##STR1## in which R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the stated meanings, and a process for the preparation thereof, are described. The stabilized compounds are suitable for the manufacture of medicinal formulations. The formula I compounds are stabilized by a polymeric protective coating before being compressed in tablet form.

Stabilized polymer film coated compounds and stabilized formulations in

Stabilized compounds of the formula I ##STR1## in which R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the stated meanings, and a process for the preparation thereof, are described. The stabilized compounds are suitable for the manufacture of medicinal formulations.

Stabilized medicinal substances, a process for the preparation thereof,

What are disclosed are secretin preparations with an intensified and protracted action, especially subcutaneously and rectally administrable preparations containing phenolic depot bodies. A process for the manufacture of the preparations and their use as well as phenolic depot bodies and the manufacture thereof are described.

Secretin preparations with intensified and protracted action, process

Ready for use, injectable, aqueous solution of a pH of from 10.2 to 11.2 containing a mixture of an alkali metal salt of canrenoic acid and furosemide without addition of a buffer and process for their preparation.

Growing community of inventors

Kelkheim, Germany

Richard Leeb