Zoetis Services LLC

Pfizer Corporation

Zoetis LLC

Pfizer Products Inc.

Zoetis P LLC

Pah USA 15 LLC

Richard Lee Krebs

Paul Joseph Dominowski

James Richard Thompson

Risini Dhammika Weeratna

Cedo Martin Bagi

Robert John Yancey, Jr

Mary Kathryn Olsen

Shucheng Zhang

Tedd Alan Childers

John Morgan Hardham

Dennis L Foss

Duncan Mwangi

Suman Mahan

Sharath K Rai

Sangita Mediratta

Shaunak Vora

Kaori Mohr

Sarah A Salmon

Guillermo Gallo

Ramasamy Mannar Mannan

Lauren Wilmes

Sandra Ann Marie Lightle

Ramasamy M Mannan

Robert John Yancey

Pamela K Klose

Pamela Kay Klose

Shelly Lynn Shields

Joseph C Frantz

Nancee Lois Oien

David George Emslie Smith

Mark D Goodyear

Michael John Huether

Anita Dorota Jaglarz

Laurel Mary Sly

Robert Greg Sorensen

Mark Davis Goodyear

Julie Lydia Fitzpatrick

Michael Christopher Fontaine

William Donachie

Corey Patrick Cook

Joseph Claude Frantz

Martin Cedo Bagi

Robert J Yancy

Nancee L Oien

The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.

Oil-based adjuvants

This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.

Adjuvant compositions

Heat treated bacterins, a method of producing heat treated bacterins, and porcine emulsion vaccines prepared from such heat treated bacterins are disclosed.

Heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins

This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.

Microfluidized oil-in-water emulsions and vaccine compositions

This invention relates to vaccines and methods for protecting dogs against disease caused by. This invention also relates to combination vaccines and methods for protecting dogs against disease or disorder caused by canine pathogens, for example, infectious tracheobronchitis caused by, canine distemper caused by canine distemper (CD) virus, infectious canine hepatitis (ICH) caused by canine adenovirus type 1 (CAV-1), respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza (CPI) virus, enteritis caused by canine coronavirus (CCV) and canine parvovirus (CPV), and leptospirosis caused byor. The vaccines of the present invention include ap68 antigen.

Canine combination vaccines

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Ashland, NE, United States of America

Richard Lee Krebs