Scios Nova, Inc.

California Biotechnology Inc.

Richard L Mitchell

Judith A Abraham

John C Fiddes

Edmund G Tischer

Isolated DNA sequences, expression vectors and transformant cells are provided which allow for the large scale production of vascular endothelial cell growth factor. The vascular endothelial cell growth factor is useful in the treatment of wounds in which neovascularization or reendothelialization is required for healing.

DNA sequences encoding bVEGF120 and hVEGF121 and methods for the

There is described an isolated vascular endothelial cell growth factor selected from the group consisting of bovine vascular endothelial cell growth factor of 120 amino acids and human vascular endothelial cell growth factor of 121 amino acids. The vascular endothelial cell growth factor is useful in the treatment of wounds in which neovascularization or reendothelialization is required for healing.

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Sunnyvale, CA, United States of America

Richard L Mitchell