Other

Manta Devices, LLC

Horsepower Technologies, Inc.

Seventh Sense Biosystems, Inc.

Mykrolis Corporation

King Systems Corporation

Boston Scientific Scimed, Inc.

Millipore Corporation

Reckitt Benckiser Inc.

Aerodesigns, Inc.

Hosso, Inc.

Manta Product Development

Jeffrey Turner

Meadow Burke, LLC

Meadow Burke Products

Richard L Miller

Andrew Jones

Christopher John Morse

Kristin Size

Gregory Scott Torrisi

Donald E Chickering, Iii

Ramin Haghgooie

Shawn Davis

Scott W James

Javier Gonzalez-Zugasti

A David Boccuti

Mark Michelman

Maisam Dadgar

Brian Hack

Daniel Scott Pflaster

Greg Fisher

Wendy Drumm

Howard Bernstein

Douglas Adam Levinson

J Karl Niermeyer

Evan Hunter Williams

Carl A Kirker-Head

Gary Vincent Palladino

Randal B Chinnock

David Lawrence Kelly

Stephen Guerrera

Peter Swai

Joseph John Crisco, Iii

Jennifer Linnane

Christopher J Wargo

Russell D Fiore

George Grubner

David J Miller

Thomas W McGrail

Jeffrey A Turner

Stephen Lee Miller

Kristin Jugenheimer Size

Yun Siung Tony Yeh

Elizabeth Powell Goodrich

Gastón De Los Reyes

Frank Scieri

Michael S Pargett

Mouli Ramani

Victoria Thompson

David A Edwards

Christopher R Deuel

Shaun Dennis Comee

Brian H Yoo

David S Baker

Stephen K Guerrera

Stephen Charles Keiser

John J Phelan

Jesse Delgigante

Elizabeth C Glass

Gaston De Los Reyes

Jose A Cruz

Paul Crosby Gregory

Jeffrey M Campbell

Angela L Miller

Gavin M McKeown

Mario Enrico Magnani

Greg Marshall

Fiorenza Bertieri

Louis C Vella

Jozef Lojko

Frank L Christy

Keith Sproat

Joseph P Phelan

Bruce Lee Baker

Benjamin Powers

Christopher R Wargo

Frances S Merrill

Patricia M Miller

Judith Di Fusco

Dennis W Woodson

Verdell Harris

Nicholas Clements

Cecily Lalor

John F Doerr

Frank Rosa

Shannon Miller

Anthony Mazzurco

Penny S Cooper

Elizabeth Goodrich

Ardite Francesc Ayats

Bosah Erike

Raymond Mincone

Matt Christiansen

John J Galvin

Keith R Wagner

Judy R Marshall

Novak Nash

Richard S Kay

Peter H Swai

Geralyn Schad

Edward C Kapraly

Ryan J Waters

Donald E Chickering Iii

The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

Inhalation device

A reconfigurable modular brush has a brush head including brush-head upper and lower surfaces extending longitudinally along a brush-head axis between brush-head first and second ends. Laterally opposed brush-head first and second sides extend between the brush-head upper and lower surfaces and longitudinally between the brush-head first and second ends. A bristle array is defined by a plurality of bristles protruding from the brush-head lower surface. A brush handle includes a grip portion and a brush-head mount, the brush handle having a lengthwise extent disposed generally along a handle axis between handle proximate and distal ends. The brush head and brush-head mount are cooperatively configured such that the handle can selectively capture and retain the brush head. Moreover, the longitudinal orientation in which the brush head is captured and retained by the brush handle is selectively reversible.

Reconfigurable modular brush and associated brush kits

An endoscopic handle attachment is adapted to be secured to an endoscope having a working channel and used in combination with a suture device adapted to extend through the working channel. The attachment includes a backbone adapted to conform to an outer surface of the endoscope and that includes one or more attachment features adapted to enable releasable securement to the endoscope. A primary arm extends radially outwardly from the backbone and includes one or attachment points, at least one of the one or more attachment points adapted to releasably secure a proximal handle of the suture device such that a translation handle may be moved relative to the proximal handle without an operator needing to separately hold the proximal handle.

Endoscopic handle attachment for use with suture based closure device

A folding staircase. The folding staircase has a frame with an upper end and a lower end. The upper end of the frame defines a top step. Multiple steps are pivotally connected to the lower end of the frame and pivoting arms connects each of the steps to one another. The frame includes brackets that secure to existing mounting points of a vehicle. At least one step is operably connected to a linear actuator, which is in turn connected to a motor. The motor is operably connected to a control switch. Activation and deactivation of the control switch causes the motor to operate resulting in the unfolding of the steps outwardly to a deployed configuration and folding inwardly to a storage configuration. The folding staircase is utilized to provide a safe method of entering and exiting a vehicle.

Folding staircase

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

Dose delivery device for inhalation

An improved joint support for limiting the range of motion of an anatomical joint comprises intermeshing gears for allowing adjustment of the range of motion of the joint, and comprises plural mechanisms for securing the gears in engagement with one another, whereby adjustment can be made without tools and without disassembly of any components.

Joint brace with improved range of motion stop

Dose delivery device with partially or fully surrounding cover may be removed to open fluid communication with a dose chamber. The cover may allow an inhaler to be stored in sterile or otherwise in a controlled environment prior to use, and removal of the cover may automatically prepare the inhaler for use.

Dose delivery device with cover connected to dose chamber seal

A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. One or more bypass inlets, two or more dispersion chambers, and/or flow arrangements in which incoming and outgoing flow in a dispersion chamber are transverse may be used to disperse a dose for delivery to a user.

Delivery device and related methods

An orthosis is fitted to a body joint, in a preferred embodiment the equine fetlock, by locating the center of rotation (COR) of the joint; measuring the bones comprising the joint at points located with respect to the COR; selecting the appropriate orthosis from a selection of models thereof; and custom-fitting the orthosis to the individual by heating it to soften a layer of thermoformable foam on the interior of the orthosis, and clamping the orthosis in place over the body joint. A kit of tools for performing the measurements is disclosed, as are a method for location of the COR of the body joint by palpation and a preferred heater.

Heater for fitting orthoses to individual body joint

An orthosis is fitted to a body joint, in a preferred embodiment the equine fetlock, by locating the center of rotation (COR) of the joint; measuring the bones comprising the joint at points located with respect to the COR; selecting the appropriate orthosis from a selection of models thereof; and custom-fitting the orthosis to the individual by heating it to soften a layer of thermoformable foam on the interior of the orthosis and clamping the orthosis in place over the body joint. A kit of tools for performing the measurements is disclosed, as are a method for location of the COR of the body joint by palpation and a preferred heater.

Tools and methods for fitting orthoses

The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.

Delivering and/or receiving fluids

The integration of drug dispersion methods into a drug or medicine delivery system may use shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The integration of a drug sealing system into the device provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

A joint-supporting device comprises tensile members extending from a proximal cuff secured to the limb above the joint to a distal cuff secured to the limb below the joint, supplementing the tensile characteristics of the joint's tendons, ligaments, and other structure. The device may also comprise structure for limiting the range of motion and angular velocity of the joint.

Limb protection device

Growing community of inventors

Needham, MA, United States of America

Richard L Miller