Obetech, LLC

Obetech Obesity Research

Richard L Atkinson

Nikhil V Dhurandhar

This invention relates to the relationship between infection with an adipogenic adenovirus, such as adenovirus-36, and obesity-related disease. In particular, this invention relates to assaying a subject to determine the adipogenic adenovirus infection status and then determining the subject's predisposition to developing an obesity-related disease based on the adipogenic adenovirus infection status.

Adipogenic adenoviruses as a biomarker for disease

Asource of viral induced obesity has been discovered. A virus known asAD-36Padenovirus type 36has been found to be associated with obesity in both animals and humans. Diagnostic DNA sequences are presented so that DNA based tests for the presence of the obesity associated virus can be conducted.

Viral obesity methods and compositions

Infection with obesifying adenoviruses in animals and humans may be used to predict changes in body weight and disease status. More particularly, infection with certain adenoviruses, such as adenovirus type 36 (Ad-36) and adenovirus type 37 (Ad-37) may cause removal of the normal equilibrium factors that control fat cell metabolism and may make individuals more responsive than normal individuals to perturbations, which cause body composition change including weight gain or weight loss.

Adenovirus status as a predictor of body composition change, disease status, and treatment outcomes

This invention relates to the relationship between infection with adipogenic adenoviruses, such as adenovirus-36 (Ad-36) and the etiologies of obesity and obesity-related cancers and other diseases. Additionally, the invention relates to assaying a subject for Ad-36 status and using Ad-36 status as a marker for the presence of cancer, to predict the future risk of developing cancers, such as breast or prostate cancer, and/or to predict the aggressiveness and prognosis of these cancers.

source of viral induced obesity has been discovered. A virus known as AD-36P has been found to be associated with obesity in both animals and humans. Diagnostic DNA sequences are presented so that DNA based tests for the presence of the obesity associated virus can be conducted.

A source of viral induced obesity has been discovered. A virus known as AD-36P has been found to be associated with obesity in both animals and humans. Diagnostic DNA sequences are presented so that DNA based tests for the presence of the obesity associated virus can be conducted.

Growing community of inventors

Mechanicsville, VA, United States of America

Richard L Atkinson