Sembiosys Genetics, Inc.

Richard Keon

Maurice M Moloney

Gijs Van Rooijen

Joseph Boothe

Cory Lee Nykiforuk

Commercial production of human insulin can be affected via transgenic expression in plant seeds. Thus, levels of insulin accumulation exceeding 0.1% of total cellular protein can be achieved recombinantly, through expression of the insulin with a single-chain antibody as a fusion partner. Production in seeds offers flexibility in storage and shipment of insulin as a raw material, and insulin retains its activity upon extraction from stored seed. Further, the amount of biomass subjected to extraction is limited, due to the relatively low water content of plant seeds.

Growing community of inventors

Calgary, Canada

Richard Keon