Glaxo Group Limited

Smithkline Beecham Corporation

Richard Jonathan Hatley

Alan D Borthwick

John Liddle

Paul Graham Wyatt

Deirdre Mary Bernadette Hickey

Andrew McMurtrie Mason

Anna Katrin Szardenings

Neil Derek Miller

Steven Leslie Sollis

David George Hubert Livermore

Fabrizio Nerozzi

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt thereof.

Substituted diketopiperazines as oxytocin antagonists

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a mammal in need thereof of an effective amount of a compound of the formula (I) and/or a physiologically acceptable derivative thereof, wherein the substituents have the meaning given in the description. Disclosed are also novel compounds of formula (I) and processes for their preparation.

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Stevenage, United Kingdom

Richard Jonathan Hatley