Codexis, Inc.

Codexis Mayflower Holdings, LLC

Maxygen, Inc.

Other

Planalytics, Inc.

Viiv Healthcare UK Limited

Richard John Fox

S Christopher Davis

Gjalt W Huisman

Jeremy S Minshull

Claes Gustafsson

Robin A Emig

Sridhar Govindarajan

Lisa Marie Newman

Phillip A Patten

Linda A Castle

Rebecca Lynne Gorton

Daniel Siehl

Anthony Cox

Teddy Chen

Emily Mundorff

Vesna Mitchell

Ranjini Chatterjee

Lorraine Joan Giver

Benjamin Mijts

Ish Kumar Dhawan

Matthew B Tobin

Anke Krebber

Birthe Borup

Martin D Eastgate

Chung-Pin H Chen

John H Grate

Frederic D Fox

Jonathan Clive Tripp

Lynne Gilson

Mitchell J Schultz

Dayne Dustan Fanfair

Thomas E La Cruz

Christina Ann Risatti

Douglas R Pearson

Maxime C Soumeillant

Christopher S Davis

Vesna Gavrilovic

Ajoy K Roy

Douglas A Hattendorf

Kenneth W Mitchell

Guy Cavet

Simon Christopher Davis

Jeffrey Colbeck

Michelle M Chen

Svetlana Balatskaya

Wendel W Doubleday

Trish Choudhary

Sabrina E Ivy

Bumshik Robert Pak

Les Partridge

Susan Y Louie

Michael S Bultman

Michael A Rhoads

Daniel L Siehl

Jeremy Minshull

Ke Chen

Phil Patten

Sridar Govindarajan

Ajoy Apt120 Roy

Rebecca Lynne Apt819 Gorton

Boguslaw M Mudryk

Saravanababu Murugesan

Joseph Francis Payack

Lorraine Jean Giver

William R Young

Daniel Held

James H Simpson

Yi Xiao

The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Methods, systems, and software for identifying functional bio-molecules

The disclosure relates to a method of generating a diverse set of variants to screen improved and novel properties within the variant population, a system for creating the diverse set of variants, and the variant peptides.

Method of generating an optimized, diverse population of variants

The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants.

Structure-activity relationships

Methods, systems, and software for identifying functional biomolecules

A knee brace includes a sleeve; and a plurality of flaps including a first lateral flap coupled to a first side of the sleeve and configured to extend toward a center of the sleeve; a second lateral flap coupled to a second side of the sleeve substantially opposite to the first side and configured to extend toward a center of the sleeve and overlap with the first transverse flap; a first transverse flap and a second transverse flap coupled to a rear side of the sleeve and configured to wrap around the first side and the second side of the sleeve, respectively, and overlap the first and second lateral flaps. Additionally, the knee brace may include a lower flap as an anterior cruciate ligament support and first and second transverse straps configured to extend over the plurality of flaps.

Knee brace

The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.

Halohydrin dehalogenases and related polynucleotides

The present disclosure relates to methods of rapidly and efficiently searching biologically-related data space to identify a population set maximally diverse and optimized for sets of desired properties. More specifically, the disclosure provides methods of identifying a diverse, evolutionary separated bio-molecules with desired properties from complex bio-molecule libraries. The disclosure additionally provides digital systems and software for performing these methods.

Computer processing methods and/or systems for minimizing and/or optimizing data strings in accordance with rules and options. Minimized data strings can represent data sequences important in certain biologic analyses and/or syntheses. In specific embodiments, a request is generated by a user at a client system and received by a server system. The server system accesses initial data indicated or provided by the client system. The server system then performs an analysis to minimize the data needed for further reactions. In specific embodiments, a server can use proprietary methods or data at the server side while protecting those proprietary methods and data from access by the client system.

Method and/or apparatus for determining codons

The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide.

Combined automated parallel synthesis of polynucleotide variants

Growing community of inventors

Redwood City, CA, United States of America

Richard John Fox