Rhomed Incorporated

The Discovery Group, LLC

Richard J Freer

Paul O Zamora

Shubh D Sharma

Buck A Rhodes

Lucian Yates Grove

A foot dorsiflexion device comprises at least one portable boot, which can be submersed in liquids if desired, worn by a patient, having a baseplate and a footplate affixed at one end to the baseplate. An inflatable bellows is positioned between the baseplate and footplate, such that inflating the bellows moves the footplate relative to the baseplate to effect flexion of the patient's foot. A controller controls the pumping sequence of a pump which can inflate one or more boot devices. In another feature, the controller also receives information as to the patient's leg muscle activity and responds appropriately to stop/re-start the device. Such a feedback mechanism is useful to prevent flexion during an abnormal contraction pattern, such as occurs in muscle spasm or tetany. The device is can be operated remotely and in both automatic and manual modes by the user or operator.

Foot flexion device

High affinity linked, branched or linear repeat peptides containing two or more biological-function domains and at least one medically useful metal ion-binding domain are labeled with medically useful metal ions for use in a variety of diseases and pathologic conditions, including diagnosis and treatment of diseases. Such peptides include high affinity chemotactic peptides containing a biological-function domain which includes at least two linked N-formyl-MLF (SEQ. ID NO. 2) sequences and high affinity repeat and branched peptides containing two or more YIGSR (SEQ. ID NO. 1) sequences.

Polyvalent peptide pharmaceutical applications

High affinity chemotactic peptides containing a biological-function domain which includes at least two linked N-formyl-Met-Leu-Phe sequences and a medically useful metal ion-binding domain are labeled with medically useful metal ions for use in a variety of diseases and pathologic conditions, and particularly for diagnosis and treatment of infections, inflammations and other diseases and conditions.

Growing community of inventors

Richmond, VA, United States of America

Richard J Freer