Sigilon Therapeutics, Inc.

Richard Heidebrecht

Robert James Miller

Omid Veiseh

Erika Ellen Johnston

Lauren Emily Barney

Matthias Alexander Oberli

Paul Kevin Wotton

David Peritt

Michael Beauregard

Guillaume Carmona

Francisco Caballero Gonzalez

Owen O'Connor

Jared A Sewell

Devyn McKinley Smith

Devyn Mckinley Smith

Owen O'CONNOR

Described herein are compositions and methods for preparing hydrogel capsules using a cross-linking solution comprising a process additive. The process additive improves the quality of the resulting hydrogel capsules, such as increasing the number of defect-free capsules.

Biocompatible hydrogel capsules and process for preparing same

Described herein are particles comprising a first compartment, a second compartment, and a compound of Formula (I), as well as compositions and methods of making and using the same. The particles may comprise a cell capable of expressing a therapeutic agent useful for the treatment of a disease, disorder, or condition described herein.

Implantable particles and related methods

The present invention provides compounds, e.g., compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are implantable elements (e.g., devices and materials) comprising the same, as well as methods of use thereof, e.g., for treating or preventing a disease, disorder, or condition.

Compounds, devices, and uses thereof

Growing community of inventors

Somerville, MA, United States of America

Richard Heidebrecht