Alcon, Inc.

Richard Govan

Yongxing Qiu

Newton T Samuel

Chung-Yuan Chiang

John Dallas Pruitt

Kelly Kayi Tallau

Ciara Dauenhauer

Kasey Jon Minick

Matthew McCollum

Matthew Mccollum

The invention is generally related to a method for producing coated silicone hydrogel contact lenses each of which has a hydrogel coating thereon and a relative high resistance to uptakes of polycationic antimicrobials as characterized by having a polyquaternium-1-uptake of less than 0.40 micrograms/lens. The hydrogel coating is formed by covalently attached a hydrophilic polymeric material onto a base coating of a polyanionic polymer on a SiHy contact lens. In this method, lower polyquaternium-1-uptake is achieved by using a rinse solution with a higher pH and/or a higher ionic strength (higher salt concentration) for rinsing a treated silicone hydrogel contact lens with a base coating of polyanionic polymer.

Method for making coated silicone hydrogel contact lenses

The invention is related to a process for producing contact lenses that not only comprise a water gradient structural configurations, but also have a minimized uptakes of polyquaternium-1 and a long-lasting surface hydrophilicity and wettability even after being undergone a simulated 30-days lens care regime.

Method for producing MPS-compatible water gradient contact lenses

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Fairburn, GA, United States of America

Richard Govan