Boston Scientific Scimed, Inc.

Synecor LLC

Barosense, Inc.

Other

Millipede, Inc.

Interventional Autonomics Corporation

Transenterix, Inc.

Neurotronik IP Holding (jersey) Limited

Transenterix Surgical, Inc.

Minimally Invasive Surgical Access Limited

Tht Consulting, LLC

Richard Glenn

Richard S Stack

Michael Scott Williams

William L Athas

Fred E Silverstein

Nathan Every

John P Lunsford

Trevor Moody

Kevin D Holbrook

Randall T Lashinski

Jeffrey A Smith

Daniel Wayne Fifer

William S Eubanks

Matthew Rust

Patrick Edward Macaulay

Geoffrey Orth

Kristian Kristoffersen

Dan Balbierz

Joseph Desimone

Daniel J Balbierz

Michael Lee

Terrance J Ransbury

Kevin H Van Bladel

Lynn H Elliott

Richard Kouri

Richard L Klein

Colleen Stack N'diaye

Padraig Savage

Nathan K Brown

Terry Wayne Daniels

Kenny Dwight Bruner

William Eubanks, Jr

William S Eubanks, Jr

Aurora Pryor

Michael S William

Ted W Layman

Stephen C Masson

Todd H Turnlund

Michael Cuchiara

Colleen Stack

Scott Purcell

Stephen C Purcell

Features for a heart valve device are described. The device may include a frame with anchors configured to secure the device to tissue. The frame may include a flared end or skirt for additional securement of the implanted device. The device may include a seal such as a barrier and/or cuff for preventing leakage. The device may contract for endovascular delivery of the device to the heart and expand for securement within the heart, such as the within the native mitral valve annulus. The device may include a replacement valve. The valve may have leaflets configured to re-direct blood flow along a primary flow axis.

Valve replacement using moveable restraints and angled struts

Systems, devices and methods related to various heart valve implants and for delivery of those heart valve implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve. The implants include a re-sizable frame having angled struts. Anchors secure the implant to tissue and collars are used to decrease the angle between the struts and contract the frame. The implant thus expands from a first size inside of a delivery catheter, to a second and larger deployed size inside the heart to engage and anchor with the tissue, and then to a third and contracted size to re-size the annulus and/or provide a secure fit for a replacement heart valve. Various delivery systems including imaging capabilities for precise delivery, positioning and anchoring of the various implants are further described.

Implantable device and delivery system for reshaping a heart valve annulus

The present disclosure includes a device for reshaping a heart valve. The device may include a central ring about a central axis and a plurality of arms coupled to the central ring, each of the arms coupled to the central ring at a pivot point at a first end of the arm, the arm comprising an attachment feature at a second point along the arm, the pivot point configured to allow movement of the arm about the pivot point through a plane extending radially from the central axis through the arm. Additionally, the plurality of arms may be contractable and may be extendable such that the hooks extend beyond a dilated heart valve. The present disclosure also includes associated methods and systems.

Systems and methods for reshaping a heart valve

Systems, devices and methods related to various heart valve implants and for delivery of those implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve. The implants include a re-sizable frame having angled struts. The implant is secured to tissue with anchors that can rotate without axial advancement to engage tissue while drawing the implant closer to the tissue. Collars are used to decrease the angle between struts of a frame to contract the implant. The implants can include a rotatable shaft, such as a threaded shaft, located internally to an axially translatable collar. Rotation of the shaft transmits force to the collar to cause the collar to translate axially, closing the angle of adjacent struts and decreasing the width of the implant and thus of the annulus. The implants can be delivered, secured and contracted via a catheter. The implants are repositionable and retrievable via catheter.

Methods related to delivery of various heart valve implants are described. The implant may be delivered using an ultrasound imaging delivery system. The ultrasound imaging delivery system may be used to deliver a variety of different devices, including mitral valve reshaping devices, mitral valve replacement valves, and others. A deployment catheter carrying an implant having a tissue anchor is advanced to a deployment site in a heart. An imaging element is positioned adjacent the implant and a relationship between the tissue anchor and an anatomical landmark in the heart is visualized. The implant is then attached by driving the tissue anchor into tissue in the heart.

Methods for delivery of heart valve devices using intravascular ultrasound imaging

Electrode systems for transvascular stimulation of target nerves include electrode arrays, elements promoting blood flow between electrode surfaces and surrounding vascular walls, electrodes shaped to promote more even current density than electrodes having angular edges, features for retaining the electrode systems with blood vessels, and features for using electrode-carrying elements to asymmetrically distend blood vessel walls towards target nerve structures.

Electrodes and electrode positioning systems for transvascular neuromodulation

Valve replacement using moveable restrains and angled struts

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Satiation devices and methods

An intravascular catheter is positionable within a blood vessel for use in transvenous stimulation of targets external to the wall of the blood vessel. The catheter includes a catheter body, a support at the distal end of the catheter body, and a plurality of electrodes carried by the support. At least a portion of the support being inflatable within the blood vessel to bias at least a portion of the plurality of electrodes into contact with the blood vessel wall.

Inflatable intravascular electrode supports for neuromodulation

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Santa Rosa, CA, United States of America

Richard Glenn