Verizon Business Global LLC

Verizon Patent and Licensing Inc.

Rockwell Collins, Inc.

Verizon UK Limited

University of Rochester

Other

Mci, Inc.

Knapp Investment Company Limited

Women & Infants Hospital of Rhode Island

Verizon Business Network Services Inc.

Mci Communications Corporation

Ol Security Limited Liability Company

Woman & Infants' Hospital of Rhode Island

Richard Garrett Moore

Duraisamy Gunasekar

Gregory Lee Mumford

Sreenivas Rachamadugu

Rakesh Kumar Singh

Maxime G G Haot

Guna Duraisamy Gunasekar

Darryl W Shaw

Lonnie Scott Clabaugh

Shawn Edward Wiederin

Jon E Abel

Kolin G Hogue

Phillip E Lawson-Shanks

Gregory L Mumsford

Geoffrey J Barnes

Frank Albert McKiel, Jr

Kaushik Raghu

Michael B Freeman

Mayel Espino

Patrick J Cosgrove

Paul A Roberts

Timothy E Darland

Charles Bradford Dirks

Anna Marie Appleby

Max Haot

David K Vognsen

Frank A Mckiel, Jr

Donald A Turner

Cory Lenger

Patrick J Dolphin

Rachael Turner

Ivan Hall

Naohiro Yano

Philip E Lawson-Shanks

Kyu K Kim

Stephen J Timm

Bryan R Vester

Christopher Lewis

The present disclosure provides novel compounds, compositions, and methods for modulating one or more septin proteins, e.g., septin-2. Such compounds and compositions are useful for the treatment of a cancer, e.g., endometrial, pancreatic, lung, breast or ovarian cancer, such as serous and ovarian clear cell carcinoma.

Septin inhibitors for treatment of cancers

The present invention provides, in certain aspects, novel 7-dehydrocholesterol (7DHC) derivatives that are useful in treating or preventing cancer, as well as in treating or preventing uncontrolled angiogenesis, in a subject. In certain embodiments of the present invention, the subject is a human. In other aspects, the present invention provides a method of preparing compounds of the invention, or a salt or solvate thereof.

7-dehydrocholesterol derivatives and methods using same

Provided herein, inter alia, are methods and compositions directed to suppressing tumor cell growth in a subject as well as methods for sensitizing a proliferating cell for treatment with a cytotoxic agent via inhibiting expression of HE4 and one or more immune checkpoint inhibitors (ICIs). Also provided herein are methods for determining whether a subject who has been diagnosed with cancer would benefit from immunotherapy as well as methods for determining whether a subject with cancer is responding to immunotherapy via assessment of levels of HE4 gene and/or protein expression.

Therapy for malignant disease

The invention provides compositions and methods for utilizing human epididymal secretion protein E4 (HE4) in the prevention and treatment of cancer and other human diseases.

HE4 based therapy for malignant disease

An approach is provided for supporting multi-media conferencing. Textual information (e.g., text associated with a presentation) is received for display during a conference session to multiple participants. For a particular participant, configuration information corresponding to the participant specifies language assistance for the textual information. Language assistance involves augmenting the textual information according to the configuration information for comprehension of the textual information by the particular participant. In one embodiment, the augmented textual information includes language translation of the textual information. Additionally, the augmented textual information can encompass definitions of terms, including acronyms. The augmented textual information is forwarded for display to the participant during the conference session.

Method and system for providing conferencing services

A method and system for dynamically personalizing an aircraft is provided. Users of an aircraft store their environmental preferences in a file on a storage device. When the users use the aircraft or ride on the aircraft, the aircraft computer system communicates with and uploads the users' files containing the users' environmental preferences. The aircraft computer system then implements the users' preferences by configuring a system of modules.

Real time and in-flight dynamic personalization of an aircraft

The present invention includes systems and methods for dynamic allocation of computing resources. Computing resources on an aircraft are divided amongst several avionics applications that are responsible for controlling sub-systems on the aircraft (e.g. the navigation system). A resource manager assigns computing resources (e.g. processor cycles) to individual applications based on the present condition of the aircraft and then instructs the throttling mechanisms to allocate the computing resources among the applications. The resource manager determines the aircraft condition by correlating inputs from the aircraft to a set of rules stored in a condition table. The resource manager then determines the computing resource allocation by correlating the aircraft condition to a set of resource allocations stored in an allocation table.

Dynamic resource allocation

A method and apparatus for controlling data transfer between a data providing device and an aircraft equipment. The method includes operating in a device mode, wherein the device mode allows the transfer of data between the data providing device and a storage medium of an intermediate device and disallows the transfer of data between the aircraft equipment and the storage medium. The method also includes operating in an avionics mode, wherein the avionics mode allows the transfer of data between the aircraft equipment and the storage medium and disallows the transfer of data between the data providing device and the storage medium. Furthermore, the method includes no more than one of operating in the device mode or operating in the avionics mode occurring at any particular time.

Smart device for controlling avionics data transfer apparatus and method

An approach provides for recording and editing digital media. A digital media stream is generated from an input signal (such as a live broadcast feed). The digital media stream is transmitted to a browser application configured to concurrently record and edit the digital media stream.

Method and system for providing a personal video recorder utilizing network-based digital media content

The present invention relates to adamantyl derivatives and their anti-cancer activity. Compounds of formulae I and II are provided as well as related methods of treatment and methods of synthesis.

Adamantyl derivatives as therapeutic agents

A messaging response system is disclosed wherein a service providing system provides services to users via messaging communications. In accordance with an exemplary embodiment of the present invention, multiple respondents servicing users through messaging communications may appear to simultaneously use a common 'screen name' identifier.

Messaging response system providing translation and conversion written language into different spoken language

An approach is provided for offering communication services supported by a data network and a telephony network. A primary identifier is assigned to a user for access to the communication services, wherein the primary identifier is used by a party seeking to communicate with the user via one of the communication services. The primary identifier is mapped to one of a plurality of secondary identifiers corresponding to the respective communication services. The one secondary identifier is used by at least one of the data network and the telephony network to establish a communication session between the party and the user.

Comprehensive communication services system

An approach provides distributed editing and storage of digital media. Video information is retrieved during recording of the video information to a video file. The video information is edited during the recording of the video information. An index file for the media is generated during the recording of the media, wherein the index file include indices for decoding the media; and periodically updating the index file throughout the recording of the media. After completion of the recording of the media, another index file is generated corresponding to the media for inclusion into the media file.

Method and system for providing distributed editing and storage of digital media over a network

Growing community of inventors

Cedar Rapids, IA, United States of America

Richard Garrett Moore