3M Innovative Properties Company

Richard G Sitz

William Blake Kolb

Peter T Benson

Gary Lee Huelsman

Nirmal K Jain

John M Sever

Kathleen M Cooklock

Method of selectively removing volatile components from a composition, comprising coating the composition onto a first substrate surface of a substrate, wherein the composition comprises a nonresident volatile component and a resident volatile component. The method further includes positioning at least a portion of the coated substrate between a condensing surface having a condensing surface temperature and a heating surface having a heating surface temperature that is greater than the condensing surface temperature, wherein the condensing surface is in a spaced apart, confronting relationship to the coated surface of the substrate and wherein the heated surface is in thermal contact with a second substrate surface opposite the first substrate surface. In the method, the heated surface temperature and the condensing surface temperature are such that the positioning step causes the nonresident volatile component to be selectively removed from the portion of the coated substrate. The method is suitable for forming transdermal drug delivery compositions.

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Woodbury, MN, United States of America

Richard G Sitz