Twelve, Inc.

Medtronic, Inc.

Richard Francis

Scott Robertson

Marian Patricia Lally

Paraic Frisby

Katherine Miyashiro

James R Keogh

Alexander J Hill

Brett R Vegoe

Curtis Goreham-Voss

Dhiraj Catoor

Marian Lally

The present technology is a prosthetic heart valve device, and related systems and methods, for treating a native valve of a human heart having a native annulus and native leaflets. One embodiment comprises a valve support, a prosthetic valve assembly within the valve support, and an anchoring member. The device further includes an extension member coupled to the anchoring member and having an annular first portion coupled to the anchoring member and a second portion coupled to the first portion. The extension member is folded in a delivery configuration such that the first portion overlaps the second portion. When released from the a delivery catheter, the extension member unfolds such that the first portion extends radially outwardly from the anchoring member and the second portion extends radially outwardly from the first portion.

Prosthetic heart valve devices and associated systems and methods

The present technology is a prosthetic heart valve device, and related systems and methods, for treating a native valve of a human heart having a native annulus and native leaflets. One embodiment comprises a valve support, a prosthetic valve assembly within the valve support, and an anchoring member having an upstream portion and a downstream portion. The device further includes an extension member coupled to the fixation frame and extending radially outward therefrom. The extension member includes a plurality of wires, at least a portion of which include an inner core surrounded by an outer material. The wires include a plurality of recesses extending through at least a portion of the thickness of the outer material, and a therapeutic agent in the recesses for delivery to the anatomy when the prosthetic heart valve device is positioned at a native annulus.

Methods for controlling properties of structural elements of implantable medical devices, where the structural elements contain shape memory alloys (SMAs) include promoting or inhibiting in vivo formation of R-phase crystal structure or converging or separating the R-phase from the austenite phase.

Shape memory articles and methods for controlling properties

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Pine Springs, MN, United States of America

Richard Francis