Inscripta, Inc.

Richard Fox

Phillip Belgrader

Andrew Garst

Don Masquelier

Bruce Chabansky

Daniel Held

Jorge Bernate

Michael Graige

Eileen Spindler

Matthew David Estes

Amy Hiddessen

Eric Abbate

Michael Clay

Katherine Krouse

Nandini Krishnamurthy

Krishna Yerramsetty

Randal M Hill

Glenn S Penny

Keith Ingram Dismuke

Andrei Zelenev

The present disclosure relates to various different types of mutations in the thrA gene inleading to enhanced lysine production for, e.g., supplements and nutraceuticals.

Rationally-designed mutations to the thrA gene for enhanced lysine production in

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods&#x2014;including high throughput methods&#x2014;for screening cells that have been subjected to editing and identifying cells that have been properly edited.

Instruments, modules, and methods for improved detection of edited sequences in live cells

The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules&#x2014;including high throughput modules&#x2014;for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.

Detection of nuclease edited sequences in automated modules and instruments

The present disclosure provides shuttle vectors for editing exogenous polynucleotides in heterologous live cells, as well as automated methods, modules, and multi-module cell editing instruments and systems for performing the editing methods.

Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells

The present disclosure relates to various different types of variants incoding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.

Genome-wide rationally-designed mutations leading to enhanced lysine production in

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Boulder, CO, United States of America

Richard Fox