Pall Corporation

Richard F Salinaro

Peter J Degen

Thomas C Gsell

Gerard R DelGiacco

Isaac Rothman

Abdoulaye Doucoure

Yoshiki Mizuno

Randy Garcez

Tony Alex

Joseph Y Lee

Ioannis P Sipsas

Moira H Bilich

Trevor A Staff

John R Gerringer

Joseph A Gregg

Non-coherent UV-treated porous halopolymer membranes are disclosed.

UV treated membranes

Devices, systems and methods for treating a biological fluid are provided comprising placing the fluid in contact with a complement filter capable of depleting at least one complement fragment from the fluid while at least one component of the biological fluid is being stored.

Biological fluid treatment system and method

A method for processing a biological fluid comprises the steps of collecting platelet-rich plasma (PRP) in a container containing a complement filter, centrifuging the PRP in the container to provide a supernatant layer comprising a volume of platelet-poor plasma (PPP) and a sediment layer including concentrated platelets, passing most of the volume of the PPP from the container, suspending the platelets in the remaining volume of PPP to provide a platelet suspension and storing the platelet suspension in the container for a storage period of at least about 24 hours while contacting the complement filter with at least a portion of the platelet suspension and removing complement from the platelet suspension.

Method for processing a biological fluid

The present invention provides an ion exchange membrane having a porous polymeric support grafted with an organic moiety to which is covalently bonded at least one ion exchange group, and methods for preparing the ion exchange membrane. A method for treating a fluid containing ions wherein ions are removed by contacting the fluid with an ion exchange membrane of the present invention is also provided. In addition, the present invention provides a filtration apparatus for removing ions from a fluid, which filtration apparatus utilizes an ion exchange membrane of the present invention.

Method of removing metal ions using an ion exchange membrane

The present invention provides a filtration medium comprising an ultrafiltration membrane and a monomer surface coating thereon of an acrylic or methacrylic acid monomer having alcohol functional groups, wherein the filtration medium after having been fully dried is characterized by having a titer reduction of at least about 10.sup.3 with respect to PP7 bacteriophage and a critical wetting surface tension of at least about 70 mN/m. The filtration medium preferably further comprises a fibrous nonwoven web embedded in the membrane. The present invention also provides a method of filtering a fluid through the present inventive filtration medium, as well as a method of preparing such a filtration medium.

Filtration medium

The present invention provides an affinity separation method involving dynamic filtration.

Affinity separation method

The present invention provides an improved method of detecting or transferring a biological material whereby a biological material is adhered to a membrane which is then contacted with a detecting reagent, wherein the improvement comprises utilizing a polyvinylidene fluoride membrane which has been subjected to a temperature of at least about 80.degree. C. but less than the temperature at which the membrane softens and deforms for a time sufficient to reduce the ability of the detecting reagent to directly adhere to the membrane.

Method of detecting biological materials using a polyvinyllidene

A PVDF membrane exposed to a quarternary ammonium hydroxide solution retains it hydrophobicity and resistance to corrosive environments, yet spontaneously and completely wets with concentrated sulfuric and nitric acids. The modified membrane is incorporated into filtration devices that are in situ integrity testable in concentrated inorganic mineral acids.

Filter device for acids and process for filtering inorganic acids

A porous chemically activated medium having a low affinity for peptide group-containing materials is provided comprising a porous polymeric medium having a low affinity for peptide group-containing materials covalently bound to a residue of an activating agent which is capable of reacting with an acceptor molecule.

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Hastings on Hudson, NY, United States of America

Richard F Salinaro