American Home Products Corporation

Wyeth

Scios Nova, Inc.

Other

Richard Eric Mewshaw

Gary Paul Stack

Thomas Joseph Commons

Dahui Zhou

Donald P Strike

Ping Zhou

James Albert Nelson

Rulin Zhao

Uresh Shantilal Shah

Kristin L Meagher

Stephen Todd Cohn

Magda Asselin

Adam Matthew Gilbert

Megan Tran

James C Keith, Jr

Heather Anne Harris

Eric Steven Manas

Leo M Albert

Deborah Ann Evrard

Cuijian Yang

Richard J Edsall

Ian A Cliffe

An Thien Vu

Young H Kang

Michael Byron Webb

George E M Husbands

Byron A Bravo

Richard James Edsall, Jr

James Carl Keith

Richard James Edsall

Aranapakam Mudumbai Venkatesan

John W Ellingboe

Ivo L Jirkovsky

Reinhardt Bernhard Baudy

Jonathan Laird Gross

George Theodore Grosu

Osvaldo Dos Santos

Lynne Padilla Greenblatt

Byron Abel Bravo

Carl Kaiser

Mira A Kanzelberger

Mary E Abreu

Stephen Marc Bowen

Gregory S Hamilton

Anthonie Johan Verwijs

Young Hee Kang

Leo Massillamoney Albert

Leo Albert

This invention provides estrogen receptor modulators of formula I having the structure where R, R, R, R, R, R, Rand Rare as defined in the specification and the use of such compounds as estrogenic agents.

Dibenzo chromene derivatives and their use as ER&#x3b2; selective ligands

This invention provides estrogen receptor modulators of formula I, having the structure wherein,

Phenyl quinolines and their use as estrogenic agents

This invention provides estrogen receptor modulators having the structure: wherein Rto Rand Rare as defined in the specification; or a pharmaceutically acceptable salt thereof.

Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents

Benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives and compositions containing such compounds are disclosed. Methods of using benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives and compositions containing such composition in the treatment and/or prevention of serotonin-related disorders, such as depression and anxiety, are also disclosed. In addition, processes for the preparation of benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives are disclosed. Benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives of Formula I are disclosed: 

Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use

This invention provides estrogen receptor modulators of formula I, having the structure where R, R, R, and Rare as defined in the specification, or a pharmaceutically acceptable salt thereof.

(Hydroxyphenyl)-1H-indole-3-carbaldehyde oxime derivatives as estrogenic agents

This invention provides estrogen receptor modulators having the structure where R&#x2013;Rare as defined in the specification; or a pharmaceutically acceptable salt thereof.

Aryl-carbaldehyde oxime derivatives and their use as estrogenic agents

This invention provides estrogen receptor modulators of formula I, having the structure where R, R, R, R, R, R, Rand Rare as defined in the specification.

This invention provides estrogen receptor modulators of formula I, having the structure wherein

Substituted phenyl naphthalenes as estrogenic agents

Compounds of the formulauseful for the treatment of depression and other conditions such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, sexual dysfunction, eating disorders, addictive disorders caused by ethanol or cocaine abuse and related illnesses.

Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan

Compounds of the formulauseful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addition, sexual dysfunction (including premature ejaculation), and related illnesses.

Antidepressant azahetorocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenathrene

Antidepressant azaheterocyclyl methyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene

This invention provides estrogen receptor modulators of formula I, having the structurewherein

Compounds of the formulauseful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as premenstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addition, sexual dysfunction (including premature ejaculation), and related illnesses.

Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene

Piperazinyl-isatins

Growing community of inventors

King of Prussia, PA, United States of America

Richard Eric Mewshaw