Sanaria Inc.

The Gillette Company

Richard E Stafford

Stephen L Hoffman

B Kim Lee Sim

Minglin Li

Antoine Kawam

Maureen Sullivan Morrissey

B Kim Sim

Disclosed are substantially purifiedsporozoites and preparations ofsporozoites substantially separated from attendant non-sporozoite material, where the preparations ofsporozoites have increasing levels of purity. Vaccines and pharmaceutical compositions comprising purifiedsporozoites are likewise provided. Methods of purifying preparations ofsporozoites are also provided.

Purified plasmodium and vaccine compositions

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Disclosed are substantially purifiedsporozoites and preparations ofsporozoites substantially separated from attendant non-sporozoite material, where the preparations ofsporozoites have increasing levels of purity. Vaccines and pharmaceutical compositions comprising purifiedsporozoites are likewise provided. Methods of purifying preparations of Plasmodium sporozoites are also provided.

The present invention provides an after shave composition comprising, by weight, 30 to 98%, preferably 65 to 95%, most preferably 70 to 90%, water, 0 to 65%, preferably 0 to 25%, most preferably 10 to 22%, ethanol, 0.25 to 6%, preferably 1 to 5%, fragrance, 0.25 to 5%, preferably 1 to 4%, surfactant to solubilize or emulsify the fragrance, and 0.5 to 1.5% (U.S.P.), preferably 0.8 to 1.3%, aluminum chlorohydrate. Preferably, the composition will be a clear solution or microemulsion having a clarity better than 100 NTU and a viscosity less than 200 mPas. The foregoing composition provides, upon application to the skin, reduced stinging and burning, reduced redness and irritation, and a soothing effect without tackiness or other undesirable aesthetic attributes.

After shave composition containing aluminum chlorohydrate

Growing community of inventors

Annandale, VA, United States of America

Richard E Stafford